The prevalence of Borrelia miyamotoi infection, and co-infections with other Borrelia spp. in Ixodes scapularis ticks collected in Canada

Particle and Fibre Toxicology

L Robbin Lindsay²  Nicholas H Ogden¹  Tyler Cote²  Antonia Dibernardo² 

[1] Public Health Agency of Canada, Zoonoses Division, Centre for Food-borne Environmental and Zoonotic Infectious Diseases, Saint-Hyacinthe, Quebec, Canada;Public Health Agency of Canada, Zoonotic Diseases and Special Pathogens, National Microbiology Laboratory, 1015 Arlington Street, Winnipeg, Manitoba, Canada

关键词: Co-infection;    Real-time PCR;    Lyme disease;    Borrelia miyamotoi;   

Others  :  807246
DOI  :  10.1186/1756-3305-7-183

 received in 2014-01-03, accepted in 2014-04-02,  发布年份 2014

【 摘 要 】

Background

Blacklegged ticks, Ixodes scapularis are vectors of the tick-borne pathogens Borrelia burgdorferi, Anaplasma phagocytophilum and Babesia microti. Recently, the I. scapularis-borne bacterium Borrelia miyamotoi has been linked to human illness in North America. The range of this tick is expanding in Canada which may increase the potential for human exposure to these agents.

Methods

In this study, 4938 I. scapularis ticks collected in 2012 were tested following a newly developed PCR-based testing protocol to determine the prevalence of infection with B. miyamotoi and other pathogens in I. scapularis in Canada.

Results

Borrelia miyamotoi was detected in blacklegged ticks from all provinces except Newfoundland, although the infection prevalence was low (<1%). There was significant variation among provinces in the prevalence of infection of ticks with B. burgdorferi and A. phagocytophilum, but not with B. miyamotoi.

Conclusions

Given the widespread distribution of B. miyamotoi, infection due to this agent should be considered in patients who have been exposed to blacklegged ticks in Canada.

【 授权许可】

   
2014 Dibernardo et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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