Extrathyroid carcinoma showing thymus-like differentiation (CASTLE): a new case report and review of the therapeutic role of neck dissection and radiotherapy

World Journal of Surgical Oncology

Dong Jin Lee²  Jin Hwan Kim²  Hye Kyung Ahn³  Mi Jung Kwon¹  Kyu Young Choi² 

[1] Department of Pathology, Hallym University College of Medicine, Hallym University Sungsim Hospital, Pyeongan-dong, Dongan-gu, Anyang-si, Gyeonggi-do 431-796, South Korea;Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Daerim-1dong, Yeongdeungpo-gu, Seoul 150-950, South Korea;Department of Pathology, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Daerim-1dong, Yeongdeungpo-gu, Seoul 150-950, South Korea

关键词: radiotherapy;    neck dissection;    thyroid gland;    CASTLE;    Carcinoma showing thymus-like differentiation;   

Others  :  1148386
DOI  :  10.1186/1477-7819-12-247

 received in 2014-05-09, accepted in 2014-07-20,  发布年份 2014

【 摘 要 】

We present here a case of extrathyroid CASTLE (the third case reported in the English literature) treated with excision and neck dissection without radiotherapy. Also, we reviewed the literature and analyzed the therapeutic results of each treatment modality for CASTLE. A 27-year-old male had initially presented with a painless, right neck mass for 2 months. Computed tomography of the neck showed a 3.8 × 3.2 × 3.8 cm heterogeneously enhancing mass at right level IIa, and no definite thyroid lesion was found. An excisional biopsy was done and the pathologic diagnosis was CASTLE. Then we performed a right modified radical neck dissection and right thyroid lobectomy. After three years, no evidence of tumor recurrence was noted. Total excision followed by neck dissection could be a sufficient surgical treatment option for CASTLE. Postoperative radiotherapy might be an alternative treatment option for neck dissection in patients with positive nodal status.

【 授权许可】

   
2014 Choi et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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