Vitamin D, allergies and asthma: focus on pediatric patients

World Allergy Organization Journal

Salvatore Tripodi⁷  Giovanni Passalacqua⁸  Giuseppe Pingitore³  Alessandro Travaglini²  Marzia Onorari⁵  Giuliana Ferrante⁴  Mariangela Bosoni⁹  Federica Bellini^1,10  Massimo Landi⁶  Auro Della Giustina¹ 

[1] Department of Pediatrics, National Healthcare System Fornovo, Parma, Italy;Aerobiological Monitoring Center, University of Tor Vergata, Rome, Italy;Allergology Unit, G.B.Grassi Hospital, Rome, Italy;Department of Sciences for Health Promotion and mother and child, University of Palermo, Palermo, Italy;Environmental Protection Agency of Tuscany (ARPAT), Department of Prato, Prato, Italy;Department of Pediatrics, National Healthcare System ASL TO1, Turin, Italy;Department of Pediatrics and Allergy Unit Sandro Pertini Hospital, Rome, Italy;Allergy and Respiratory Diseases, IRCCS San Martino-Ist-University of Genoa, Pad. Maragliano, L.go R Benzi 10, 16133 Genoa, Italy;Pediatric Unit, G. Fornaroli Hospital, Magenta, Milan, Italy;Pediatric Unit Department of Gynecologic, Obstetric and Pediatric Sciences, University of Bologna, Bologna, Italy

关键词: Pediatric allergy;    Rhinitis;    Asthma;    Supplementation;    Immunomodulation;    Allergic diseases;    Vitamin D;   

Others  :  1137525
DOI  :  10.1186/1939-4551-7-27

 received in 2014-07-02, accepted in 2014-09-11,  发布年份 2014

【 摘 要 】

In recent years, the interest of the scientific world towards vitamin D gradually increased, and several studies have been conducted to dissect its possible role in modulating the development/course of allergic diseases. Also, Vitamin D supplementation has been assessed as a beneficial approach for treating allergies in some, but not all studies. We reviewed herein the available and relevant literature concerning the possible links between Vitamin D, its supplementation and allergic diseases. A literature search was made independently by the Authors, identifying articles for a narrative review. As per literature, Vitamin D plays a key role in calcium and phosphate metabolism, and it is essential for bone health in infants, children and adolescents. However, there is presently insufficient evidence to support vitamin D supplementation for prevention or treatment of allergic diseases in infants, children and adolescents, concerning allergic rhinitis, asthma, food allergy and atopic dermatitis.

【 授权许可】

   
2014 Della Giustina et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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