Phylogenetic relationships of the glycoprotein gene of bovine ephemeral fever virus isolated from mainland China, Taiwan, Japan, Turkey, Israel and Australia

Virology Journal

Changqing Qiu¹  Fuying Zheng¹ 

[1] State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Yanchangbao, Lanzhou, 730046, China

关键词: Variation;    Phylogenetic relationship;    Mainland China;    Glycoprotein gene;    Bovine ephemeral fever virus;   

Others  :  1153195
DOI  :  10.1186/1743-422X-9-268

 received in 2012-04-06, accepted in 2012-11-12,  发布年份 2012

【 摘 要 】

Background

The glycoprotein (G) gene sequences of bovine ephemeral fever virus (BEFV) strains derived from mainland China have not been compared with those of the isolates from other countries or areas. Therefore, the G genes of four BEFV isolates obtained from mainland China were amplified and sequenced. A phylogenetic tree was constructed in order to compare and analyze the genetic relationships of the BEFV isolates derived from mainland China and different countries and areas.

Results

The complete BEFV G gene was successfully amplified and sequenced from four isolates that originated from mainland China. A total of fifty-one BEFV strains were analyzed based on the G gene sequence and were found to be highly conserved. A phylogenetic tree showed that the isolates were grouped into three distinct lineages depending on their source of origin. The antigenic sites of G₁, G₂ and G₃ are conserved among the isolates, except for several substitutions in a few strains.

Conclusions

The phylogenetic relationships of the BEFV isolates that originated from mainland China, Taiwan, Japan, Turkey, Israel and Australia were closely related to their source of origin, while the antigenic sites G₁, G₂ and G₃ are conserved among the BEFV isolates used in this work.

【 授权许可】

   
2012 Zheng and Qiu; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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