期刊论文详细信息
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Factors correlating with delayed trauma center admission following traumatic brain injury
Markus B Skrifvars1  Jaakko Lappalainen3  Tuomas Brinck2  Markku Kuisma1  Riku Kivisaari3  Jari Siironen3  Rahul Raj3 
[1] Department of Anesthesiology, Intensive Care, Emergency Care and Pain management, Helsinki University Central Hospital, Helsinki, Finland;Department of Orthopedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland;Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland
关键词: Emergency medical service;    Outcome;    Triage;    Transport;    Pre-hospital;    Traumatic brain injury;   
Others  :  810762
DOI  :  10.1186/1757-7241-21-67
 received in 2013-05-10, accepted in 2013-09-08,  发布年份 2013
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【 摘 要 】

Background

Delayed admission to appropriate care has been shown increase mortality following traumatic brain injury (TBI). We investigated factors associated with delayed admission to a hospital with neurosurgical expertise in a cohort of TBI patients in the intensive care unit (ICU).

Methods

A retrospective analysis of all TBI patients treated in the ICUs of Helsinki University Central Hospital was carried out from 1.1.2009 to 31.12.2010. Patients were categorized into two groups: direct admission and delayed admission. Patients in the delayed admission group were initially transported to a local hospital without neurosurgical expertise before inter-transfer to the designated hospital. Multivariate logistic regression was utilized to identify pre-hospital factors associated with delayed admission.

Results

Of 431 included patients 65% of patients were in the direct admission groups and 35% in the delayed admission groups (median time to admission 1:07h, IQR 0:52–1:28 vs. 4:06h, IQR 2:53–5:43, p <0.001). In multivariate analysis factors increasing the likelihood of delayed admission were (OR, 95% CI): male gender (3.82, 1.60-9.13), incident at public place compared to home (0.26, 0.11-0.61), high energy trauma (0.05, 0.01-0.28), pre-hospital physician consultation (0.15, 0.06-0.39) or presence (0.08, 0.03-0.22), hypotension (0.09, 0.01-0.93), major extra cranial injury (0.17, 0.05-0.55), abnormal pupillary light reflex (0.26, 0.09-0.73) and severe alcohol intoxication (12.44, 2.14-72.38). A significant larger proportion of patients in the delayed admission group required acute craniotomy for mass lesion when admitted to the neurosurgical hospital (57%, 21%, p< 0.001). No significant difference in 6-month mortality was noted between the groups (p= 0.814).

Conclusion

Delayed trauma center admission following TBI is common. Factors increasing likelihood of this were: male gender, incident at public place compared to home, low energy trauma, absence of pre-hospital physician involvement, stable blood pressure, no major extra cranial injuries, normal pupillary light reflex and severe alcohol intoxication. Focused educational efforts and access to physician consultation may help expedite access to appropriate care in TBI patients.

【 授权许可】

   
2013 Raj et al.; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Jennett B: Epidemiology of head injury. J Neurol Neurosurg Psychiatr 1996, 60:362-369.
  • [2]Sasser SM, Hunt RC, Faul M, Sugerman D, Pearson WS, Dulski T, Wald MM, Jurkovich GJ, Newgard CD, Lerner EB, Centers for Disease Control and Prevention (CDC): Guidelines for field triage of injured patients: recommendations of the national expert panel on field triage. MMWR Recomm Rep 2011, 2012:1-20.
  • [3]Badjatia N, Carney N, Crocco TJ, Fallat ME, Hennes HMA, Jagoda AS, Jernigan S, Letarte PB, Lerner EB, Moriarty TM, Pons PT, Sasser S, Scalea T, Schleien CL, Wright DW, Brain Trauma Foundation, BTF Center for Guidelines Management: Guidelines for prehospital management of traumatic brain injury 2nd edition. Prehosp Emerg Care 2008, 12(Suppl 1):S1-S52.
  • [4]Fakhry SM, Trask AL, Waller MA, Watts DD, IRTC Neurotrauma Task Force: Management of brain-injured patients by an evidence-based medicine protocol improves outcomes and decreases hospital charges. J Trauma 2004, 56:492-499. discussion 499–500
  • [5]Hartl R, Gerber LM, Iacono L, Ni Q, Lyons K, Ghajar J: Direct transport within an organized state trauma system reduces mortality in patients with severe traumatic brain injury. J Trauma 2006, 60:1250-1256. discussion 1256
  • [6]Stiver SI, Manley GT: Prehospital management of traumatic brain injury. Neurosurg Focus 2008, 25:E5.
  • [7]Myburgh JA, Cooper DJ, Finfer SR, Venkatesh B, Jones D, Higgins A, Bishop N, Higlett T, Australasian Traumatic Brain Injury Study (ATBIS) Investigators for the Australian, New Zealand Intensive Care Society Clinical Trials Group: Epidemiology and 12-month outcomes from traumatic brain injury in australia and new zealand. J Trauma 2008, 64:854-862.
  • [8]Berry C, Ley EJ, Margulies DR, Mirocha J, Bukur M, Malinoski D, Salim A: Correlating the blood alcohol concentration with outcome after traumatic brain injury: too much is not a bad thing. Am Surg 2011, 77:1416-1419.
  • [9]Lindberg L, Brauer S, Wollmer P, Goldberg L, Jones AW, Olsson SG: Breath alcohol concentration determined with a new analyzer using free exhalation predicts almost precisely the arterial blood alcohol concentration. Forensic Sci Int 2007, 168:200-207.
  • [10]Maas AIR, Marmarou A, Murray GD, Teasdale SGM, Steyerberg EW: Prognosis and clinical trial design in traumatic brain injury: the IMPACT study. J Neurotrauma 2007, 24:232-238.
  • [11]Perel P, Arango M, Clayton T, Edwards P, Komolafe E, Poccock S, Roberts I, Shakur H, Steyerberg E, Yutthakasemsunt S, MRC CRASH Trial Collaborators: Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. BMJ 2008, 336:425-429.
  • [12]Maas AIR, Hukkelhoven CWPM, Marshall LF, Steyerberg EW: Prediction of outcome in traumatic brain injury with computed tomographic characteristics: a comparison between the computed tomographic classification and combinations of computed tomographic predictors. Neurosurgery 2005, 57:1173-1182. discussion 1173–82
  • [13]Baker SP, O’Neill B, Haddon W, Long WB: The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma 1974, 14:187-196.
  • [14]Steyerberg EW, Mushkudiani N, Perel P, Butcher I, Lu J, McHugh GS, Murray GD, Marmarou A, Roberts I, Habbema JDF, Maas AIR: Predicting outcome after traumatic brain injury: development and international validation of prognostic scores based on admission characteristics. PLoS Med 2008, 5:e165. Discussion e165
  • [15]MacKenzie EJ, Rivara FP, Jurkovich GJ, Nathens AB, Frey KP, Egleston BL, Salkever DS, Scharfstein DO: A national evaluation of the effect of trauma-center care on mortality. N Engl J Med 2006, 354:366-378.
  • [16]Patel HC, Bouamra O, Woodford M, King AT, Yates DW, Lecky FE, Trauma Audit and Research Network: Trends in head injury outcome from 1989 to 2003 and the effect of neurosurgical care: an observational study. Lancet 2005, 366:1538-1544.
  • [17]Moen KG, Klepstad P, Skandsen T, Fredriksli OA, Vik A: Direct transport versus interhospital transfer of patients with severe head injury in Norway. Eur J Emerg Med 2008, 15:249-255.
  • [18]Sampalis JS, Denis R, Fréchette P, Brown R, Fleiszer D, Mulder D: Direct transport to tertiary trauma centers versus transfer from lower level facilities: impact on mortality and morbidity among patients with major trauma. J Trauma 1997, 43:288-295. discussion 295–6
  • [19]Hannan EL, Farrell LS, Cooper A, Henry M, Simon B, Simon R: Physiologic trauma triage criteria in adult trauma patients: are they effective in saving lives by transporting patients to trauma centers? J Am Coll Surg 2005, 200:584-592.
  • [20]Seelig JM, Becker DP, Miller JD, Greenberg RP, Ward JD, Choi SC: Traumatic acute subdural hematoma: major mortality reduction in comatose patients treated within four hours. N Engl J Med 1981, 304:1511-1518.
  • [21]Haselsberger K, Pucher R, Auer LM: Prognosis after acute subdural or epidural haemorrhage. Acta Neurochir (Wien) 1988, 90:111-116.
  • [22]Wright KD, Knowles CH, Coats TJ, Sutcliffe JC: “Efficient” timely evacuation of intracranial haematoma–the effect of transport direct to a specialist centre. Injury 1996, 27:719-721.
  • [23]Stone JL, Lowe RJ, Jonasson O, Baker RJ, Barrett J, Oldershaw JB, Crowell RM, Stein RJ: Acute subdural hematoma: direct admission to a trauma center yields improved results. J Trauma 1986, 26:445-450.
  • [24]Brain Trauma Foundation, American Association of Neurological Surgeons, Congress of Neurological Surgeons: Guidelines for the management of severe traumatic brain injury. J Neurotrauma 2007, 24(Suppl 1):S1-S106.
  • [25]Shahin H, Gopinath SP, Robertson CS: Influence of alcohol on early glasgow coma scale in head-injured patients. J Trauma 2010, 69:1176-1181. discussion 1181
  • [26]Smits M, Dippel DWJ, Steyerberg EW, de Haan GG, Dekker HM, Vos PE, Kool DR, Nederkoorn PJ, Hofman PAM, Twijnstra A, Tanghe HLJ, Hunink MGM: Predicting intracranial traumatic findings on computed tomography in patients with minor head injury: the CHIP prediction rule. Ann Intern Med 2007, 146:397-405.
  • [27]Stiell IG, Wells GA, Vandemheen K, Clement C, Lesiuk H, Laupacis A, McKnight RD, Verbeek R, Brison R, Cass D, Eisenhauer ME, Greenberg G, Worthington J: The Canadian CT head rule for patients with minor head injury. Lancet 2001, 357:1391-1396.
  • [28]Haydel MJ, Preston CA, Mills TJ, Luber S, Blaudeau E, DeBlieux PM: Indications for computed tomography in patients with minor head injury. N Engl J Med 2000, 343:100-105.
  • [29]Goldschlager T, Rosenfeld JV, Winter CD: “Talk and die” patients presenting to a major trauma centre over a 10 year period: a critical review. J Clin Neurosci 2007, 14:618-623. discussion 624
  • [30]Marshall LF, Toole BM, Bowers SA: The national traumatic coma data bank: part 2: patients who talk and deteriorate: implications for treatment. J Neurosurg 1983, 59:285-288.
  • [31]Tagliaferri F, Compagnone C, Korsic M, Servadei F, Kraus J: A systematic review of brain injury epidemiology in Europe. Acta Neurochir (Wien) 2006, 148:255-268. discussion 268
  • [32]Savola O, Niemelä O, Hillbom M: Alcohol intake and the pattern of trauma in young adults and working aged people admitted after trauma. Alcohol Alcohol 2005, 40:269-273.
  • [33]Chen CM, Yi H-Y, Yoon Y-H, Dong C: Alcohol use at time of injury and survival following traumatic brain injury: results from the National Trauma Data Bank. J Stud Alcohol Drugs 2012, 73:531-541.
  • [34]Andelic N, Jerstad T, Sigurdardottir S, Schanke A-K, Sandvik L, Roe C: Effects of acute substance use and pre-injury substance abuse on traumatic brain injury severity in adults admitted to a trauma centre. J Trauma Manag Outcomes 2010, 4:6. BioMed Central Full Text
  • [35]Kool B, Ameratunga S, Jackson R: The role of alcohol in unintentional falls among young and middle-aged adults: a systematic review of epidemiological studies. Inj Prev 2009, 15:341-347.
  • [36]Pöyry T, Luoto TM, Kataja A, Brander A, Tenovuo O, Iverson GL, Ohman J: Acute assessment of brain injuries in ground-level falls. J Head Trauma Rehabil 2013, 28(2):89-97.
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