Assessment of ovarian reserve using anti-Müllerian hormone levels in benign gynecologic conditions and surgical interventions: a systematic narrative review

Reproductive Biology and Endocrinology

Fumitaka Kikkawa²  Maki Goto²  Tatsuo Nakahara²  Tomoko Nakamura²  Akira Iwase¹ 

[1] Department of Maternal and Perinatal Medicine, Nagoya University Hospital, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan;Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan

关键词: UAE;    Ovarian reserve;    Endometriosis;    Cystectomy;    AMH;   

Others  :  1132319
DOI  :  10.1186/1477-7827-12-125

 received in 2014-09-24, accepted in 2014-12-14,  发布年份 2014

【 摘 要 】

The usefulness of anti-Müllerian hormone (AMH) for the quantitative evaluation of ovarian reserve has been established. Therefore, serum AMH has been recently applied to the assessment of ovarian reserve outside infertility treatment. We conducted a computer-based search, using keywords, through the PubMed database from inception until May 2014 and summarized available studies evaluating ovarian damage caused by gynecologic diseases, such as endometriosis and ovarian tumor, as well as surgical interventions, such as cystectomy and uterine artery embolization (UAE), to discuss the usefulness of serum AMH. Most of the studies demonstrated a decline of serum AMH levels after cystectomy for endometriomas. It is not conclusive whether electrocoagulation or suturing is preferable. The effects of other gynecologic diseases and interventions, such as hysterectomy and UAE, on ovarian reserve are controversial. Serum AMH levels should be considered in determining the indication and selection of operative methods for benign gynecologic conditions.

【 授权许可】

   
2014 Iwase et al.; licensee BioMed Central.

【 图 表 】

Figure 1.

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