Obstructive sleep apnea and vascular disease

Respiratory Research

Virend A Somers¹  Paola Lanfranchi¹ 

[1] Mayo Clinic, Rochester, Minnesota, USA

关键词: vascular disease;    sympathetic nervous system;    sleep apnea;    hypertension;    cardiovascular risk;   

Others  :  1227429
DOI  :  10.1186/rr79

 received in 2001-04-23, accepted in 2001-07-19,  发布年份 2001

【 摘 要 】

There is emerging evidence linking obstructive sleep apnea (OSA) to vascular disease, including hypertension. This relationship may be independent of co-morbidity, such as obesity. Even apparently healthy OSA patients have evidence of subtle functional vascular abnormalities that are known to occur in patients with hypertension and atherosclerosis. Untreated OSA may possibly contribute to the initiation and/or progression of pathophysiologic mechanisms involved in hypertension, heart failure, cardiac ischemia and stroke. This brief commentary will examine the evidence and mechanisms linking OSA to vascular disease.

【 授权许可】

   
2001 BioMed Central Ltd

【 图 表 】

Figure 1.

Figure 2.

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