期刊论文详细信息
World Allergy Organization Journal
Anaphylaxis as a Manifestation of Horse Allergy
Lawrence DuBuske1  Tomas Pitsch2  Radoslaw Gawlik2 
[1] Immunology Research Institute of New England, Harvard, MA;Department and Clinic of Internal and Allergic Diseases and Clinical Immunology, Silesian University School of Medicine, Zabrze, Poland
关键词: horse;    allergy;    anaphylaxis;   
Others  :  1180834
DOI  :  10.1097/WOX.0b013e3181b2fe51
PDF
【 摘 要 】

Allergic disease induced by animal exposure is a common phenomenon worldwide. Whereas cat and dog dander exposure are well recognized as causative of allergic rhinitis, allergic asthma, and contact urticaria, horse allergy can present with anaphylaxis. Horse allergy is induced by exposure to the major horse allergens Equ 1 through 5. The severity of the symptoms may be related to the level of exposure. Greatest risk of anaphylaxis occurs in those sensitized patients who have large amounts of animal allergen exposure, such as when in a barn, or when an animal bite occurs exposing sensitized persons to large quantities of the animal allergen that resides in the saliva. Horse allergy may be successfully treated with allergen specific immunotherapy.

【 授权许可】

   
2009 World Allergy Organization; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150514101037414.pdf 224KB PDF download
【 参考文献 】
  • [1]Chapman MD, Wood RA: The role and remediation of animal allergens in allergic diseases. J Allergy Clin Immunol 2001, 107:414-421.
  • [2]Roberts G, Lack G: Horse allergy in children. BMJ 2000, 321:286-287.
  • [3]Roberts G, Peckitt C, Northstone K, et al.: Relationship between aeroallergen and food allergen sensitization in childhood. Clin Exp Allergy 2005, 35:933-940.
  • [4]Almqvist C, Larrson PH, Egmar A-C, Hedren M, Malmberg P, Wickman M: School as a risk environment for children allergic to cats and a site for transfer of cat allergen to homes. J Allergy Clin Immunol 1999, 103:1012-1017.
  • [5]Riedler J, Eder W, Oberfeld G, Schreuer M: Austrian children living on a farm have less hay fever, asthma and allergic sensitisation. Clin Exp Allergy 2000, 30:194-200.
  • [6]Kilpelainen M, Terho EO, Helenius H, Koskenvuo M: Farm environment in childhood prevents development of allergies. Clin Exp Allergy 2000, 30:201-208.
  • [7]Ernst P, Cormier Y: Relative scarcity of asthma and atopy among rural adolescents raised on a farm. Am J Respir Crit Care Med 2000, 161:1563-1566.
  • [8]Ownby DR, Johnson CC, Peterson EL: Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA 2002, 288:963-972.
  • [9]Platts-Mills T, Vaughan J, Squillace S, et al.: Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population based cross-sectional study. Lancet 2001, 357:752-756.
  • [10]Goubran Botros H, Poncet P, Rabillon J, Fontaine T, Laval JM, David B: Biochemical characterization and surfactant properties of horse allergens. Eur J Biochem 2001, 268:3126-3136.
  • [11]Egglestone PA, Ansari AA, Adkinson NF, Wood RA: Environmental challenge studies laboratory animal allergy. Am J Respir Crit Care Med 1995, 151:640-646.
  • [12]Aoyama K, Ueda A, Manda F, Matsushita T, Ueda T, Yamauchi C: Allergy to laboratory animals: an epidemiologic study. Br J Ind Med 1992, 49:41-47.
  • [13]Gregoire C, Rosinski-Chupin I, Rabillon J, et al.: cDNA cloning and sequencing reveal the major horse allergen Equ c 1 to be a glycoprotein member of lipocalin superfamily. J Biol Chem 1996, 271:32951-32959.
  • [14]Lowenstein H, Markussen B, Weeke B: Isolation and partial characterization of three major allergens of horse hair and dandruff. Int Arch Allergy Appl Immunol 1976, 51:4867.
  • [15]Goubran Botros H, Rabillon J, Gregoire C, David B, Dandeu JP: J Chromatogr B Thiophilic adsorption chromatography: purification of Equ c2 and Equ c3, two horse allergens from horse sweat. Biomed Sci Appl 1998, 710:57-65.
  • [16]Goubran Botros H, Gregoire C, Rabillon J, David B, Dandeu JP: Cross-antigenicity of horse serum albumins: study of tree short peptides with significant inhibitory activity towards specific human IgE and IgG antibodies. Immunology 1996, 88:340-347.
  • [17]Spitzauer S, Pandjaitan B, Soregi G, Mühl S, Ebner C, et al.: IgE cross-reactivities against albumins in patients allergic to animals. J Allergy Clin Immunol 1995, 96:951-959.
  • [18]Virtanen T, Zeiler T, Mantyjarvi R: Important animal allergens are lipocalin proteins: why are they allergenic? Int Arch Allergy Immunol 1999, 120:247-258.
  • [19]Felix K, Ferrandiz R, Einarsson R, Dreborg S: Allergens of horse dander: comparison among breeds and individual animals by immuno-blotting. J Allergy Clin Immunol 1996, 98:169-171.
  • [20]Egmar AC, Almqvist C, Emenius G, Lilja G, Wickman M: Deposition of cat (Fel d1), dog (Can f1), and horse allergen over time in public environments a model of dispersion. Allergy 1998, 53:957-961.
  • [21]Emenius G, Larsson PH, Wickman M, Härfast B: Dispersion of horse allergen in the ambient air, detected with sandwich ELISA. Allergy 2001, 56:771-774.
  • [22]Fernandez-Tavora L, Rico P, Martin S: Clinical experience with specific immunotherapy to horse dander. J Investig Allergol Clin Immunol 2002, 12:29-33.
  • [23]Savalainen J, et al.: IgE response to fur animal allergens and domestic animal allergens in fur farmers and fur garment workers. Clin Exp Allergy 1997, 27:5-12.
  • [24]Tutluoglu B, Atis S, Anakkaya AN, Altug E, Tosun GA, Yaman M: Sensitization to horse hair, symptoms and lung function in grooms. Clin Exp Allergy 2002, 32:1170-1173.
  • [25]Lelong M, Castelain MC, Bras C, et al.: An outbreak of allergy to horses in children. A review of 56 recent cases. Pediatrie 1992, 47:55-58.
  • [26]van der Mark S: Contact urticaria from horse saliva. Contact Dermatitis 1983, 9:145.
  • [27]Guida G, Nebiolo F, Heffler E, Bergia R, Rolla G: Anaphylaxis after horse bite. Allergy 2005, 60:1088-1089.
  • [28]van der Heide S, van Aalderen WM, Kauffman HF, Dubois AE, de Monchy JG: Clinical effects of air cleaners in homes of asthmatic children sensitized to pet allergens. J Allergy Clin Immunol 1999, 104:447-451.
  • [29]Nelson HS: Advances in upper airway diseases and allergen immunotherapy. J Allergy Clin Immunol 2005, 115:676-684.
  文献评价指标  
  下载次数:14次 浏览次数:18次