期刊论文详细信息
World Allergy Organization Journal
Serum Interleukin-18 Expression in Children With Bronchial Asthma
Sherif R Moussa1  Eman S El-Hadidi2  Shereen S El-Sayed1  Elham M Hossny1 
[1] Department of Pediatrics, Cairo, Egypt;Department of Clinical Pathology, Ain Shams University, Cairo, Egypt
关键词: pathogenesis;    exacerbation;    inflammation;    children;    asthma;    IL-18;   
Others  :  1180886
DOI  :  10.1097/WOX.0b013e3181a33649
PDF
【 授权许可】

   
2009 World Allergy Organization; licensee BioMed Central Ltd.

【 预 览 】
附件列表
Files Size Format View
20150514101603520.pdf 559KB PDF download
【 参考文献 】
  • [1]Imboden M, Nicod L, Nieters A, Glaus E, Matyas G, et al.: The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study. Clin Exp Allergy 2006, 36:211-218.
  • [2]Eaton AD, Xu D, Garside P: Administration of exogenous interleukin-18 and interleukin-12 prevents the induction of oral tolerance. Immunology 2003, 108:196-203.
  • [3]El-Mezayen RE, Matsumoto T: In vitro responsiveness to IL-18 in combination with IL-12 or IL-2 by PBMC from patients with bronchial asthma and atopic dermatitis. Clin Immunol 2004, 111:61-68.
  • [4]El-Mezzein RE, Matsumoto T, Nomiyama H, Miike T: Increased secretion of IL-18 in vitro by peripheral blood mononuclear cells of patients with bronchial asthma and atopic dermatitis. Clin Exp Immunol 2001, 126:193-198.
  • [5]Jung T, Witzak K, Dieckhoff K, Zachmann K, Heidrich S, Aversa G, et al.: IFN-g is only partially restored by co-stimulation with IL-12, IL-2, IL-15, IL-18 or engagement of CD28. Clin Exp Allergy 1999, 29:207-216.
  • [6]Hata H, Yoshimoto T, Hayashi N, Hada T, Nakanishi K: IL-18 together with anti-CD3 antibody induces human Th1 cells to produce Th1- and Th2-cytokines and IL-8. Int Immunol 2004, 16:1733-1739.
  • [7]Komai-Koma M, Gracie JA, Wei XQ, Xu D, Thomson N, McInnes IB, Liew FY: Chemoattraction of human T cells by IL-18. J Immunol 2003, 170:1084-1090.
  • [8]Kohka H, Yoshino T, Iwagaki H, Sakuma I, Tanimoto T, et al.: Interleukin-18/interferon-gamma-inducing factor, a novel cytokine, up-regulates ICAM-1 (CD54) expression in KG-1 cells. J Leukoc Biol 1998, 64:519-527.
  • [9]Ohtsuki T, Micallef MJ, Kohno K, Tanimoto T, Ikeda M, Kurimoto M: Interleukin-18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells. Anticancer Res 1997, 17:3253-3258.
  • [10]Lewkowich IP, HayGlass KT: Endogenous IFN-gamma and IL-18 production directly limit induction of type 2 immunity in vivo. Eur J Immunol 2002, 32:3536-3545.
  • [11]Lee KS, Kim SR, Park SJ, Min KH, Lee KY, et al.: Antioxidant down-regulates interleukin-18 expression in asthma. Mol Pharmacol 2006, 70:1184-1193.
  • [12]Tsutsui H, Yoshimoto T, Hayashi N, Mizutani H, Nakanishi K: Induction of allergic inflammation by interleukin-18 in experimental animal models. Immunol Rev 2004, 202:115-138.
  • [13]Yoshimoto T, Nakanishi K: Roles of IL-18 in basophils and mast cells. Allergol Int 2006, 55:105-113.
  • [14]American Thoracic Society: Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987, 136:225-244.
  • [15]National Institutes of Health. National Heart Lung and Blood Institutes: National Asthma Education and Prevention Program: Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma - Update on Selected Topics 2002. Available at: http://www.nhlbi.nih.gov/guidelines/archives/epr-2_upd/index.htm webcite. Accessed March 27, 2009
  • [16]Geaghan SM: Normal blood values: selected reference values for neonatal, pediatric and adult populations. In Hematology basic principles and practice. 3rd edition. Edited by Hoffman R, Benz EJ, Shattil SJ, Furie B, Cohen HJ, et al.. Philadelphia: Churchill Livingstone; 2000:2520-2528.
  • [17]Cebeci AN, Nuhoglu Y, Arslanoglu I, Erguven M, Agachan N: The role of IL-18 in Th1/Th2 balance in children. Allergy Asthma Proc 2006, 27:365-370.
  • [18]Ho LP, Davis M, Denison A, Wood FT, Greening AP: Reduced interleukin-18 levels in BAL specimens from patients with asthma compared to patients with sarcoidosis and healthy control subjects. Chest 2002, 121:1421-1426.
  • [19]Bohn E, Sing A, Zumbihl R, Bielfeldt C, Okamura H, et al.: IL-18 (IFN-gamma inducing factor) regulates early cytokine production in, and promotes resolution of, bacterial infection in mice. J Immunol 1998, 160:299-307.
  • [20]Cameron L, Taha R, Tsicopoulos A, Kurimoto M, Olivenstein R, et al.: Airway epithelium expresses interleukin-18. Eur Respir J 1999, 14:553-559.
  • [21]Ando M, Shima M: Serum interleukins 12 and 18 and immunoglobulin E concentrations and allergic symptoms in Japanese schoolchildren. J Investig Allergol Clin Immunol 2007, 17:14-19.
  • [22]Xue YN, Zou XD, Wu JL: [Correlation of serum IL-16, IL-18 levels and immunoglobulins in children with asthma]. Zhongguo Dang Dai Er Ke Za Zhi 2006, 8:6-8.
  • [23]Wong CK, Ho CY, Ko FW, Chan CH, Ho AS, Hui DS, Lam CW: Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-gamma, IL-4, IL-10 and IL-13) in patients with allergic asthma. Clin Exp Immunol 2001, 125:177-183.
  • [24]Kim SW, Jeon YK, Won TB, Dhong HJ, Min JY, Shim WS, Min YG: Effects of corticosteroids on expression of interleukin-18 in the airway mucosa of a mouse model of allergic rhinitis. Ann Otol Rhinol Laryngol 2007, 116:76-80.
  • [25]McKay A, Komai-Koma M, MacLeod KJ, Campbell CC, Kitson SM, et al.: Interleukin-18 levels in induced sputum are reduced in asthmatic and normal smokers. Clin Exp Allergy 2004, 34:904-910.
  • [26]Hofstra CL, Van Ark I, Hofman G, Kool M, Nijkamp FP, Van Oosterhout AJ: Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels. J Immunol 1998, 161:5054-5060.
  • [27]Kumano K, Nakao A, Nakajima H, Hayashi F, Kurimoto M, et al.: Interleukin-18 enhances antigen-induced eosinophil recruitment into the mouse airways. Am J Respir Crit Care Med 1999, 160:873-878.
  • [28]Wild JS, Sigounas A, Sur N, Siddiqui MS, Alam R, Kurimoto M, Sur S: IFN-gamma-inducing factor (IL-18) increases allergic sensitization, serum IgE, Th2 cytokines, and airway eosinophilia in a mouse model of allergic asthma. J Immunol 2000, 164:2701-2710.
  • [29]Kodama T, Matsuyama T, Kuribayashi K, Nishioka Y, Sugita M, et al.: IL-18 deficiency selectively enhances allergen-induced eosinophilia in mice. J Allergy Clin Immunol 2000, 105:45-53.
  • [30]Campbell E, Kunkel SL, Strieter RM, Lukacs NW: Differential roles of IL-18 in allergic airway disease: induction of eotaxin by resident cell populations exacerbates eosinophil accumulation. J Immunol 2000, 164:1096-1102.
  • [31]Matsubara S, Takeda K, Kodama T, Joetham A, Miyahara N, et al.: IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells. Am J Respir Cell Mol Biol 2007, 36:324-332.
  • [32]Hoshino T, Yagita H, Ortaldo J, Wiltrout R, Young H: In vivo administration of IL-18 can induce IgE production through Th2 cytokine induction. Eur J Immunol 2000, 30:1998-2006.
  文献评价指标  
  下载次数:10次 浏览次数:20次