First description of Trypanosoma cruzi human infection in Esmeraldas province, Ecuador

Particle and Fibre Toxicology

Mariella Anselmi⁴  Francisco Robinzon¹  Cynthia Caicedo¹  Rosanna Prandi¹  Varsovia Cevallos²  Marcia Racines³  Sandra Vivero³  Hipatia Criollo³  Juan Moreira¹  Ángel Guevara³ 

[1]CECOMET, Nelson Estupiñan Bass 210 y Luis Tello, Esmeraldas, Ecuador

[2]Instituto Nacional de Investigación en Salud Pública, Entomología, Ministerio de Salud del Ecuador, Sodiro y Yaguachi, Quito, Ecuador

[3]Laboratorio de Parasitologia Molecular y Medicina Tropical, Centro de Biomedicina, Carrera de Medicina, Universidad Central del Ecuador, Sodiro N14121 e Iquique, Quito, Ecuador

[4]Centro de Enfermedades Tropicales, Hospital Sacro Cuore, Verona, Negrar, Italia

关键词: Chagas disease;    Awá population;    Esmeraldas;    Ecuador;    Trypanosoma cruzi;    Triatoma dispar L;   

Others  :  1181878
DOI  :  10.1186/1756-3305-7-358

 received in 2014-06-12, accepted in 2014-07-16,  发布年份 2014

【 摘 要 】

Chagas disease was described in Ecuador in 1930 in the province of Guayas and thereafter in various provinces. Triatomine were reported in the province of Esmeraldas but no human infection has been described. Here we report the first evidence that the disease does exist in the province of Esmeraldas. In indigenous Awá communities located in the northwest jungle of the Esmeraldas province, 144 individuals were tested using ELISA and PCR for T.cruzi of which 5 (3.47%) were positive. Twenty eight triatomine were collected, 27 were Triatoma dispar and 1 Pastrongylus rufotuberculatus, T.cruzi was detected in 11 (42.3%) of 26 insects.

【 授权许可】

   
2014 Guevara et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

【 参考文献 】

• [1]Bonney K: Chagas disease in the 21st century: a public health success or an emerging threat? Parasite 2014, 21:11.
• [2]Aguilar M, Abad–Franch F, Racines J, Paucar A: Epidemiology of Chagas disease in Ecuador. A brief review. Mem Inst Oswaldo Cruz 1999, 94:387-393.
• [3]Arteaga C: Investigaciones sobre la existencia de la enfermedad de Chagas en la zona del ferrocarril de la Costa (Provincia del Guayas). Rev Univ Guayaquil 1930, 1:89-101.
• [4]Guevara A, Garzón E, Bowen C, Córdova X, Gómez E, Ouaissi A: High infection rates of Triatoma dimidiata are associated with low levels of Trypanosoma cruzi seroprevalence in Pedro Carbo, Ecuador: Use of a tc24 gene-based PCR approach. Parasite 2005, 12:65-68.
• [5]Smith B, Conlan C, Hwang W, Weirauch C: Polymerase Chain Reaction Detection of Trypanosoma cruzi in Suboptimally Preserved Vectors and Comparative Infection Rates 2007–2010 in Escondido Southern California. Vector-Borne Zoonotic Dis 2011, 11(12):1603-1604.
• [6]Guevara A, Eras J, Recalde M, Vinueza L, Cooper P, Ouassi A, Guderian R: Severe digestive pathology associated with chronic Chagas disease in Ecuador: report of two cases. Rev Soc Bras Med Trop 1997, 30:389-392.
• [7]Kirchhoff L, Votava J, Ochs D, Moser D: Comparison of PCR and microscopic methods for detecting Trypanosoma cruzi. J Clin Microb 1996, 34(5):1171-1175.
• [8]Zeledon R, Ugalde J, Paniagua L: Entomological and Ecological Aspects of Six Sylvatic Species of Triatomines (Hemiptera, Reduviidae) from the Collection of the National Biodiversity Institute of Costa Rica, Central America. Mem Inst Oswaldo Cruz Rio de Janeiro 2001, 96(6):757-764.
• [9]Grijalva M, Villacís A, Ocaña S, Yumiseva C, Baus E: Limitations of selective deltamethrin application for triatomine control in central coastal Ecuador. Parasites & Vectors 2011, 4:20. BioMed Central Full Text