New Allergens of Relevance in Tropical Regions: The Impact of Ascaris lumbricoides Infections

World Allergy Organization Journal

Nathalie Acevedo²  Luis Caraballo¹ 

[1] Institute for Immunological Research, University of Cartagena, Cartagena, Colombia;Foundation for the Development of Medical and Biological Sciences, Cartagena, Colombia

关键词: Asc l 3;    ABA-1;    asthma;    hygiene hypothesis;    Ascaris;   

Others  :  1145610
DOI  :  10.1097/WOX.0b013e3182167e04

【 摘 要 】

One of the many aspects of the relationships between parasite infections and allergic diseases is the possibility that allergens from parasites enhance the T_H2 responses, especially IgE production, in allergic diseases such as asthma. In this review we discuss about the allergenic composition of the nematode Ascaris lumbricoides and their potential impact on allergy sensitization and asthma pathogenesis and prevalence in populations living in the tropics and naturally exposed to both, mite allergens and helminth infections.

【 授权许可】

   
2011 World Allergy Organization; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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