The value of Serum BNP for diagnosis of intracranial injury in minor head trauma

World Journal of Emergency Surgery

Cihat Yel¹  Fatih Alagoz¹  Mehmet Ali Ceyhan¹  Tamer Durdu¹  Fevzi Yilmaz¹  Muhittin Serkan Yilmaz¹  Cemil Kavalci²  Ali Demir¹ 

[1] Emergency Department, Numune Training and Research Hospital, Ankara 06370, Turkey;Emergency Department, Baskent University Faculty of Medicine, Ankara 06450, Turkey

关键词: Brain natriuretic peptide;    Head trauma;    Emergency;   

Others  :  791395
DOI  :  10.1186/1749-7922-9-16

 received in 2014-01-06, accepted in 2014-02-09,  发布年份 2014

【 摘 要 】

Objective

Head injury is the main cause of death among individuals younger than 45 years old. Cranial Computerized tomography (CT) is commonly used for diagnosis of head injury. Brain Natriuretic Peptide (BNP) is a peptide originally isolated from brain ventricles. The main aim of this study is to investigate BNP as an indicator of head injury among patients presenting to emergency department (ED) with minor head trauma.

Methods

This was a prospective study conducted at the emergency department of the Numune Training and Research Hospital. A total of 162 patients who presented to the ED with minor head injury were enrolled. The patients were categorized into 2 groups as the cranial CT-negative and positive groups. The normality of the data was tested using One Sample Kolmogorov Smirnov test. Mann–Whitney U test was used to compare 2 independent groups while the Kruskal-Wallis test was utilized for comparison of more than 2 groups. A p-value of <0.05 was considered to be significant.

Results

Ninety-six (59.3%) patients were male and 66 (40.7%) were female. The cranial CT-negative group had a median BNP level of 14.5 pg/ml while the cranial CT-positive group had a median BNP level of 13 pg/ml. There was no statistically significant difference between these two groups for serum BNP levels (p > 0.05).

Conclusion

This study suggested that serum BNP level wasn’t used in defined of intracranial injury.

【 授权许可】

   
2014 Demir et al.; licensee BioMed Central Ltd.

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