Clinical application of ultrasound-guided core needle biopsy with multiple punches in the diagnosis of lymphoma

World Journal of Surgical Oncology

Qin Zhang³  Xudong Chen⁵  Xiaohong Xu¹  Bosheng He²  Yanggui Xie⁴  Xiuzhen Ji³  Ying He³ 

[1] Department of Oncology, The Cancer Hospital of Nantong University, No. 30 Tongyang North Road, Pingchao Town, Tongzhou District, Nantong 226361, China;Department of Radiology, The Second Affiliated Hospital of Nantong University, No.6 Hai Er Xiang North Road, Nantong 226001, Jiangsu, P.R. China;Department of Ultrasound, The Cancer Hospital of Nantong University, No. 30 Tongyang North Road, Pingchao Town, Tongzhou District, Nantong 226361, China;Department of Ultrasound, The First Affiliated Hospital of Nantong University, No. 20 Xisi Road, Nantong 226001, China;Department of Pathology, The Cancer Hospital of Nantong University, No. 30 Tongyang North Road, Pingchao Town, Tongzhou District, Nantong 226361, China

关键词: Accuracy rate;    Multiple punches;    Core needle biopsy;    Ultrasound-guided;    Lymphoma;   

Others  :  1145993
DOI  :  10.1186/s12957-015-0537-2

 received in 2014-12-19, accepted in 2015-03-07,  发布年份 2015

【 摘 要 】

Background

The purpose of this study is to investigate the feasibility, accuracy, and limitations of ultrasound (US)-guided core needle biopsy (CNB) with multiple punches in the diagnosis of lymphoma in the whole body.

Methods

From March 2007 to October 2013, US-guided CNB with multiple punches was performed by well-experienced radiologists in 110 patients (CNB group), and surgical biopsy was carried out in 95 patients (surgical group). The differences of accuracy rate between the two groups in the diagnosis of lymphoma and its subtypes were examined with Fisher’s exact test.

Results

There were no statistical differences between the CNB group and the surgical group in the diagnostic accuracy rate of lymphoma, as well as its subtypes in superficial and deep masses. In addition, in the CNB group, there were no statistical differences between different lengths of lesions in the diagnosis accuracy rate of lymphoma and its subtypes.

Conclusions

US-guided CNB with no less than three punches is an accurate, safe, minimally invasive, non-radiological, fast, and cost-effective method in the evaluation of lymphoma and its subtypes as compared with surgical approach. It should be considered as the acceptable alternative to surgical biopsy to obtain histopathological samples in the patients with suspected lymphoma.

【 授权许可】

   
2015 He et al.; licensee BioMed Central.

【 图 表 】

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