Association of House Dust Allergen Concentrations With Residential Conditions in City and in Rural Houses

World Allergy Organization Journal

Marek L Kowalski¹  Tomasz Gwardys¹  Marzanna Jarzębska¹  Magdalena Kaczała¹  Leszek Korzon²  Jolanta Pełka³  Barbara Majkowska-Wojciechowska¹  Aleksandra Wardzyńska¹ 

[1] Department of Immunology, Rheumatology and Allergy, Medical University of Lodz, Lodz, Poland;Allergy Center, Slupia, Poland;Allergy Center 'Medyk', Wielun, Poland

关键词: residential conditions;    allergy;    dog allergen;    cat allergen;    house dust mite;    allergen concentration;   

Others  :  1137713
DOI  :  10.1097/WOX.0b013e3182447fa8

【 摘 要 】

Background

The aim of the study was to evaluate the relationship between house dust mite, cat and dog allergen levels with household characteristics in the houses of children living in urban and rural areas in central Poland.

Methods

Dust samples were collected from 141 urban and 191 rural houses. Der f1 + Der p1, Can f 1, and Fel d1 levels were measured and associated with residential conditions and atopy-related health outcomes assessed by clinical examination and skin prick testing.

Results

Concentrations of mite allergens were lower, and cat and dog allergen levels were higher in urban houses. Fel d1 and Can f1 levels depended on the presence of a respective animal in the house. In urban houses, Der p1 + Der f1 concentration was lower in households with central heating, whereas Can f1 concentration was related to building age. Multivariate analyses revealed that the concentrations of house dust mite and dog allergens were associated with relative humidity, number of people in the household, and the presence of a dog at home. There was no significant association between allergen level and sensitization or atopic diseases.

Conclusions

Concentrations of indoor allergens in urban and rural houses differ significantly, and residential conditions associated with allergen levels seem to be different in both environments.

【 授权许可】

   
2012 World Allergy Organization; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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