Role of gammadelta T cells in protecting normal airway function

Respiratory Research

Erwin W Gelfand¹  Rebecca L O'Brien¹  Arihiko Kanehiro¹  Katsuyuki Takeda¹  Michael Lahn¹  Willi K Born¹ 

[1] National Jewish Medical and Research Center, Denver, Colorado, USA

关键词: lymphocytes;    airway hyper-responsiveness;    asthma;    γδ T cells;   

Others  :  1227477
DOI  :  10.1186/rr26

 received in 2000-08-18, accepted in 2000-09-27,  发布年份 2000

【 摘 要 】

Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.

【 授权许可】

   
2000 Current Science Ltd

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