Delay in diagnosis of cancer as a patient safety issue - a root cause analysis based on a representative case report

Patient Safety in Surgery

Tun Oo²  Paul Mansour¹  Peter L Hughes³  Gurpreet Singh⁴  Bakul M Soni²  Subramanian Vaidyanathan² 

[1] Department of Cellular Pathology, District General Hospital, Town Lane, Southport, Merseyside PR8 6PN, UK;Regional Spinal Injuries Centre, Town Lane, Southport, Merseyside PR8 6PN, UK;Department of Radiology, District General Hospital, Town Lane, Southport, Merseyside PR8 6PN, UK;Department of Urology, District General Hospital, Town Lane, Southport, Merseyside PR8 6PN, UK

关键词: Cystoscopy;    Suprapubic cystostomy;    Carcinoma;    Urinary bladder;    Spinal cord injury;   

Others  :  790391
DOI  :  10.1186/1754-9493-5-19

 received in 2011-06-03, accepted in 2011-07-29,  发布年份 2011

【 摘 要 】

Background

It is well known in the literature that imaging has almost no value for diagnosis of superficial bladder cancer. However, wide gap exists between knowledge on diagnosis of bladder cancer and actual clinical practice.

Case presentation

Delay in diagnosis of bladder cancer in a male person with tetraplegia occurred because of reliance on negative flexible cystoscopy and single biopsy, negative ultrasound examination of urinary bladder, and computerised tomography of pelvis. Difficulties in scheduling cystoscopy also contributed to a delay of nearly ten months between the onset of haematuria and establishing a histological diagnosis of vesical malignancy in this patient. The time interval between transurethral resection and cystectomy was 42 days. This delay was mainly due to scheduling of surgery.

Conclusion

We learn from this case that doctors should be aware of the limitations of negative flexible cystoscopy and single biopsy, cytology of urine, ultrasound examination of urinary bladder, and computed tomography of pelvis for diagnosis of bladder cancer in spinal cord injury patients. Random bladder biopsies must be considered under general anaesthesia when there is high suspicion of bladder cancer. Spinal cord injury patients with lesions above T-6 may develop autonomic dysreflexia; therefore, one should be extremely well prepared to prevent or manage autonomic dysreflexia when performing cystoscopy and bladder biopsy. Spinal cord injury patients, who pass blood in urine, should be accorded top priority in scheduling of investigations and surgical procedures.

【 授权许可】

   
2011 Vaidyanathan et al; licensee BioMed Central Ltd.

【 图 表 】

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