期刊论文详细信息
World Journal of Surgical Oncology
Primary medulla oblongata germinomas: two case reports and review of the literature
Liwei Zhang1  Junting Zhang1  Zhen Wu1  Liang Wang1  Jie Feng2  Da Li1  Shuyu Hao1 
[1] Department Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, NO.6 Tiantan Xili Dongcheng district, Beijing 100050, P R China;Beijing Neurosurgical Institute, Capital Medical University, NO.6 Tiantan Xili Dongcheng district, Beijing 100050, P R China
关键词: Treatment;    Medulla oblongata;    Germinoma;   
Others  :  821211
DOI  :  10.1186/1477-7819-11-274
 received in 2013-02-02, accepted in 2013-09-20,  发布年份 2013
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【 摘 要 】

An intracranial germinoma is a tumor that is sensitive to radiotherapy. As medulla oblongata germinomas are extremely rare, determining an accurate preoperative diagnosis is challenging. Two cases of medulla oblongata lesions were surgically treated, and a postoperative diagnosis of germinoma was determined in both of the cases. The tumor in one patient completely resolved after a treatment course consisting of surgical intervention, radiotherapy and chemotherapy; the other patient, who did not receive any type of adjuvant treatment after surgery, suffered from tumor relapse and died from pneumonia 8 months following surgery. A preoperative diagnosis of medulla oblongata germinoma is difficult because of the lack of specific clinical signs and symptoms. If the correct diagnosis is reached, patients can have a favorable prognosis with proper evaluation and treatment. An invasive operation can potentially lesion and impair the function of the medulla oblongata, which is fatal to the patient.

【 授权许可】

   
2013 Hao et al.; licensee BioMed Central Ltd.

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