Nutrition & Metabolism | |
Dairy consumption and cardiometabolic health: outcomes of a 12-month crossover trial | |
Karen J Murphy1  Alison M Coates1  Jonathan D Buckley1  Peter R C Howe1  Georgina E Crichton1  | |
[1] Nutritional Physiology Research Centre, University of South Australia, GPO Box 2471, Adelaide, South Australia 5001, Australia | |
关键词: Cardiometabolic health; Obesity; Milk; Dairy; | |
Others : 820011 DOI : 10.1186/1743-7075-9-19 |
|
received in 2011-10-09, accepted in 2012-03-20, 发布年份 2012 | |
【 摘 要 】
Background
A growing body of research suggests that regular consumption of dairy foods may counteract obesity and other components of the metabolic syndrome. However, human intervention trials are lacking. We aimed to determine the cardiometabolic health effects of increasing the consumption of reduced fat dairy foods in adults with habitually low dairy intakes in the absence of energy restriction.
Methods
An intervention trial was undertaken in 61 overweight or obese adults who were randomly assigned to a high dairy diet (HD, 4 serves of reduced fat dairy/day) or a low dairy control diet (LD, ≤1 serve/day) for 6 months then crossed over to the alternate diet for a further 6 months. A range of anthropometric and cardiometabolic parameters including body composition, metabolic rate, blood lipids, blood pressure and arterial compliance were assessed at the end of each diet phase.
Results
Total energy intake was 1120 kJ/day higher during the HD phase, resulting in slight weight gain during this period. However, there were no significant differences between HD and LD in absolute measures of waist circumference, body weight, fat mass or any other cardiometabolic parameter.
Conclusion
Recommended intakes of reduced fat dairy products may be incorporated into the diet of overweight adults without adversely affecting markers of cardiometabolic health.
Trial Registration
The trial was registered with the Australia and New Zealand Clinical Trials Registry (ACTRN12608000538347) on 24th October, 2008.
【 授权许可】
2012 Crichton et al; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
20140712022036680.pdf | 341KB | download | |
Figure 1. | 34KB | Image | download |
【 图 表 】
Figure 1.
【 参考文献 】
- [1]Heber D: An integrative view of obesity. Am J Clin Nutr 2010, 91:280S-283S.
- [2]Colagiuri S, Lee CM, Colagiuri R, Magliano D, Shaw JE, Zimmet PZ, Caterson ID: The cost of overweight and obesity in Australia. Med J Aust 2010, 192:260-264.
- [3]Finkelstein EA, Fiebelkorn IC, Wang G: State-level estimates of annual medical expenditures attributable to obesity. Obes Res 2004, 12:18-24.
- [4]Elwood PC: Time to value milk. Int J Epidemiol 2005, 34:1160-1162.
- [5]Zemel MB, Richards J, Mathis S, Milstead A, Gebhardt L, Silva E: Dairy augmentation of total and central fat loss in obese subjects. Int J Obes (Lond) 2005, 29:391-397.
- [6]Zemel MB, Teegarden D, Van Loan MD, Schoeller DA, Matkovic V, Lyle RM, Craig BA: Dairy-rich diets augment fat loss on an energy-restricted diet: a multicenter trial. Nutrients 2009, 1:83-100.
- [7]Zemel MB, Thompson W, Milstead A, Morris K, Campbell P: Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obes Res 2004, 12:582-590.
- [8]Bowen J, Noakes M, Clifton PM: A high dairy protein, high-calcium diet minimizes bone turnover in overweight adults during weight loss. J Nutr 2004, 134:568-573.
- [9]Harvey-Berino J, Gold BC, Lauber R, Starinski A: The impact of calcium and dairy product consumption on weight loss. Obes Res 2005, 13:1720-1726.
- [10]Thompson WG: Rostad Holdman N, Janzow DJ, Slezak JM, Morris KL, Zemel MB: Effect of energy-reduced diets high in dairy products and fiber on weight loss in obese adults. Obes Res 2005, 13:1344-1353.
- [11]Lanou AJ, Barnard ND: Dairy and weight loss hypothesis: an evaluation of the clinical trials. Nutr Rev 2008, 66:272-279.
- [12]Baran D, Sorensen A, Grimes J, Lew R, Karellas A, Johnson B, Roche J: Dietary modification with dairy products for preventing vertebral bone loss in premenopausal women: a three-year prospective study. J Clin Endocrinol Metab 1990, 70:264-270.
- [13]Chee WS, Suriah AR, Chan SP, Zaitun Y, Chan YM: The effect of milk supplementation on bone mineral density in postmenopausal Chinese women in Malaysia. Osteoporos Int 2003, 14:828-834.
- [14]Cleghorn DB, O'Loughlin PD, Schroeder BJ, Nordin BE: An open, crossover trial of calcium-fortified milk in prevention of early postmenopausal bone loss. Med J Aust 2001, 175:242-245.
- [15]Devine A, Prince RL, Bell R: Nutritional effect of calcium supplementation by skim milk powder or calcium tablets on total nutrient intake in postmenopausal women. Am J Clin Nutr 1996, 64:731-737.
- [16]Gunther CW, Legowski PA, Lyle RM, McCabe GP, Eagan MS, Peacock M, Teegarden D: Dairy products do not lead to alterations in body weight or fat mass in young women in a 1-y intervention. Am J Clin Nutr 2005, 81:751-756.
- [17]Nowson CA, Worsley A, Margerison C, Jorna MK, Godfrey SJ, Booth A: Blood pressure change with weight loss is affected by diet type in men. Am J Clin Nutr 2005, 81:983-989.
- [18]Wong SY, Lau EM, Lau WW, Lynn HS: Is dietary counselling effective in increasing dietary calcium, protein and energy intake in patients with osteoporotic fractures? A randomized controlled clinical trial. J Hum Nutr Diet 2004, 17:359-364.
- [19]Zemel MB, Richards J, Milstead A, Campbell P: Effects of calcium and dairy on body composition and weight loss in African-American adults. Obes Res 2005, 13:1218-1225.
- [20]Barr SI, McCarron DA, Heaney RP, Dawson-Hughes B, Berga SL, Stern JS, Oparil S: Effects of increased consumption of fluid milk on energy and nutrient intake, body weight, and cardiovascular risk factors in healthy older adults. J Am Diet Assoc 2000, 100:810-817.
- [21]Lau EM, Woo J, Lam V, Hong A: Milk supplementation of the diet of postmenopausal Chinese women on a low calcium intake retards bone loss. J Bone Miner Res 2001, 16:1704-1709.
- [22]Azadbakht L, Mirmiran P, Esmaillzadeh A, Azizi T, Azizi F: Beneficial effects of a Dietary Approaches to Stop Hypertension eating plan on features of the metabolic syndrome. Diabetes Care 2005, 28:2823-2831.
- [23]Steffen LM, Kroenke CH, Yu X, Pereira MA, Slattery ML, Van Horn L, Gross MD, Jacobs DR Jr: Associations of plant food, dairy product, and meat intakes with 15-y incidence of elevated blood pressure in young black and white adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Clin Nutr 2005, 82:1169-1177.
- [24]Wang L, Manson JE, Buring JE, Lee IM, Sesso HD: Dietary intake of dairy products, calcium, and vitamin D and the risk of hypertension in middle-aged and older women. Hypertension 2008, 51:1073-1079.
- [25]Choi HK, Willett WC, Stampfer MJ, Rimm E, Hu FB: Dairy consumption and risk of type 2 diabetes mellitus in men: a prospective study. Arch Intern Med 2005, 165:997-1003.
- [26]Liu S, Choi HK, Ford E, Song Y, Klevak A, Buring JE, Manson JE: A prospective study of dairy intake and the risk of type 2 diabetes in women. Diabetes Care 2006, 29:1579-1584.
- [27]Azadbakht L, Mirmiran P, Esmaillzadeh A, Azizi F: Dairy consumption is inversely associated with the prevalence of the metabolic syndrome in Tehranian adults. Am J Clin Nutr 2005, 82:523-530.
- [28]Elwood PC, Pickering JE, Fehily AM: Milk and dairy consumption, diabetes and the metabolic syndrome: the Caerphilly prospective study. J Epidemiol Community Health 2007, 61:695-698.
- [29]Lutsey PL, Steffen LM, Stevens J: Dietary intake and the development of the metabolic syndrome. The Atherosclerosis Risk in Communities Study. Circulation 2008, 117:754-761.
- [30]Mennen LI, Lafay L, Feskens EJM, Novak M, Lepinay P, Balkau B: Possible protective effect of bread and dairy products on the risk of metabolic syndrome. Nutr Res 2000, 20:335-347.
- [31]Pereira MA, Jacobs DR Jr, Van Horn L, Slattery ML, Kartashov AI, Ludwig DS: Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study. JAMA 2002, 287:2081-2089.
- [32]Crichton GE, Bryan J, Buckley J, Murphy KJ: Dairy consumption and metabolic syndrome: a systematic review of findings and methodological issues. Obes Rev 2011. doi 10.1111/j.1467-789X.2010.00837.x
- [33]National Nutrition Survey: Foods Eaten Australia [http:/ / www.ausstats.abs.gov.au/ Ausstats/ subscriber.nsf/ 0/ CA25687100069892CA256888001CD460/ $File/ 48040_1995.pdf] webcite 1995.
- [34]Dietary Guidelines for Australian Adults [http://www.nhmrc.gov.au/publications/synopses/_files/n33.pdf] webcite
- [35]National Health Survey: summay of results [http:/ / www.abs.gov.au/ ausstats/ abs@.nsf/ Latestproducts/ 4364.0Main%20Features42007-2008%20% 28Reissue%29?opendocument&tabname=S ummary&prodno=4364.0&issue=2007-200 8%20%28Reissue%29&num=&view=] webcite
- [36]Jones B: Kenward MG: Design and analysis of cross-over trials. 2nd edition. Boca Raton, Florida: Chapman & Hall/CRC; 2003.
- [37]Altman DG: Statistics and ethics in medical research: III How large a sample? British Medical Journal 1980, 281:1336-1338.
- [38]Marfell-Jones M, Olds T, Stewart A, Carter L: International standards for anthropometric assessment. Revthth edition. Potchefstroom, South Africa: International Society for the Advancement of Kinanthropometry; 2006.
- [39]Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
- [40]Giles GG, Ireland PD: Dietary Questionnaire for Epidemiological Studies (Version 2). Melbourne: The Cancer Council Victoria; 1996.
- [41]Hodge A, Patterson AJ, Brown WJ, Ireland P, Giles G: The Anti Cancer Council of Victoria FFQ: Relative validity of nutrient intakes compared with weighed food records in young to middle-aged women in a study of iron supplementation. Aust N Z J Public Health 2000, 24:576-583.
- [42]Xinying PX, Noakes M, Keogh J: Can a food frequency questionnaire be used to capture dietary intake data in a 4 week clinical intervention trial? Asia Pac J Clin Nutr 2004, 13:318-323.
- [43]Ambrosini GL, van Roosbroeck SAH, Mackerras D, Fritschi L, de Klerk NH, Musk AW: The reliability of ten-year dietary recall: Implications for cancer research. J Nutr 2003, 133:2663-2668.
- [44]Bouchard C, Tremblay A, Leblanc C, Lortie G, Savard R, Theriault G: A method to assess energy expenditure in children and adults. Am J Clin Nutr 1983, 37:461-467.
- [45]Zemel MB, Donnelly JE, Smith BK, Sullivan DK, Richards J, Morgan-Hanusa D, Mayo MS, Sun X, Cook-Wiens G, Bailey BW, Van Walleghen EL, Washburn RA: Effects of dairy intake on weight maintenance. Nutr Metab (Lond) 2008, 5:28. BioMed Central Full Text
- [46]Lin YC, Lyle RM, McCabe LD, McCabe GP, Weaver CM, Teegarden D: Dairy calcium is related to changes in body composition during a two-year exercise intervention in young women. J Am Coll Nutr 2000, 19:754-760.
- [47]Gunther CW, Lyle RM, Legowski PA, James JM, McCabe LD, McCabe GP, Peacock M, Teegarden D: Fat oxidation and its relation to serum parathyroid hormone in young women enrolled in a 1-y dairy calcium intervention. Am J Clin Nutr 2005, 82:1228-1234.
- [48]Melanson EL, Donahoo WT, Dong F, Ida T, Zemel MB: Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans. Obes Res 2005, 13:2102-2112.
- [49]Melanson EL, Sharp TA, Schneider J, Donahoo WT, Grunwald GK, Hill JO: Relation between calcium intake and fat oxidation in adult humans. Int J Obes Relat Metab Disord 2003, 27:196-203.
- [50]Teegarden D, White KM, Lyle RM, Zemel MB, Van Loan MD, Matkovic V, Craig BA, Schoeller DA: Calcium and dairy product modulation of lipid utilization and energy expenditure. Obesity (Silver Spring) 2008, 16:1566-1572.
- [51]Zemel MB: Role of calcium and dairy products in energy partitioning and weight management. Am J Clin Nutrition 2004, 79:907S-912S.
- [52]Zemel MB: The role of dairy foods in weight management. J Am Coll Nutr 2005, 24:537S-546S.
- [53]Jacobsen R, Lorenzen JK, Toubro S, Krog-Mikkelsen I, Astrup A: Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion. Int J Obes (Lond) 2005, 29:292-301.
- [54]Welberg JWM, Monkelbaan JF, Devries EGE, Muskiet FAJ, Cats A, Oremus E, Boersmavanek W, Vanrijsbergen H, Vandermeer R, Mulder NH, Kleibeuker JH: Effects of supplemental dietary calcium on quantitative and qualitative fecal fat excretion in man. Ann Nutr Metab 1994, 38:185-191.
- [55]Denke MA, Fox MM, Schulte MC: Short-term dietary calcium fortification increases fecal saturated fat content and reduces serum lipids in men. J Nutr 1993, 123:1047-1053.
- [56]Hilpert KF, West SG, Bagshaw DM, Fishell V, Barnhart L, Lefevre M, Most MM, Zemel MB, Chow M, Hinderliter AL, Kris-Etherton PM: Effects of dairy products on intracellular calcium and blood pressure in adults with essential hypertension. J Am Coll Nutr 2009, 28:142-149.
- [57]Toledo E, Delgado-Rodriguez M, Estruch R, Salas-Salvado J, Corella D, Gomez-Gracia E, Fiol M, Lamuela-Raventos RM, Schroder H, Aros F, Ros E, Ruiz-Gutierrez V, Lapetra J, Conde-Herrera M, Saez G, Vinyoles E, Martinez-Gonzalez MA: Low-fat dairy products and blood pressure: follow-up of 2290 older persons at high cardiovascular risk participating in the PREDIMED study. Br J Nutr 2009, 101:59-67.
- [58]van Meijl LEC, Mensink RP: Low-fat dairy consumption reduces systolic blood pressure, but does not improve other metabolic risk parameters in overweight and obese subjects. Nutr Metab Cardiovasc Dis 2011, 21:355-361.
- [59]van Meijl LEC, Mensink RP: Effects of low-fat dairy consumption on markers of low-grade systemic inflammation and endothelial function in overweight and obese subjects: an intervention study. Br J Nutr 2010, 104:1523-1527.
- [60]Wennersberg MH, Smedman A, Turpeinen AM, Retterstol K, Tengblad S, Lipre E, Aro A, Mutanen P, Seljeflot I, Basu S, Pedersen JI, Mutanen M, Vessby B: Dairy products and metabolic effects in overweight men and women: results from a 6-mo intervention study. Am J Clin Nutr 2009, 90:960-968.
- [61]Nutrient Reference Values for Australia and New Zealand [http://www.nhmrc.gov.au/publications/synopses/_files/n35.pdf] webcite
- [62]Livingstone MBE: Assessment of food intakes - are we measuring what people eat? Br J Biomed Sci 1995, 52:58-67.