Weight changes in Portuguese patients with depression: which factors are involved?

Nutrition Journal

Paula Ravasco¹  Jerónima Correia² 

[1] Laboratório de Nutrição da Faculdade de Medicina da Universidade de Lisboa e Hospital Universitário de Santa Maria, Avenida Prof. Egas Moniz, 1649-028 Lisbon, Portugal;Psychiatric Department of the Hospital da Nossa Senhora do Rosário – EPE, Barreiro, Portugal

关键词: Psychiatric drugs;    Physical activity;    Food intake;    Weight changes;    Nutrition;    Depression;   

Others  :  1132390
DOI  :  10.1186/1475-2891-13-117

 received in 2013-12-11, accepted in 2014-11-14,  发布年份 2014

【 摘 要 】

Background &Aims

Depression may lead to obesity, just as obesity can contribute to the disease; yet, changes in the dietary pattern and food habits in depressive syndromes have been scantily investigated. We aimed to identify possible associations between nutritional factors and depressive disorder.

Methods

This cross sectional study included 127 consecutive ambulatory adult patients with depression (DSM-IV), under psychiatric treatment. All study parameters were classified according to sex & age: BMI, waist circumference, %fat mass, food intake & physical activity.

Results

Patients’ mean age was 48 ± 13 (18–81) yrs, 94% were women. Overweight/obesity was found in 72% of the cohort, 72% had excessive fat mass & 69% had a waist circumference above the maximum cut-off value. Longer disease was associated with higher BMI +%fat mass, p < 0.003. Weight gain during illness was registered in 87%; just 12% lost weight, though undernutrition did not occur. Weight gain and greater fat mass were related with higher BMI, p = 0.002. The pattern of food intake was poor, monotonous and inadequate in 59% of patients; there was also a regular consumption of hypercaloric foods by 78% pts. Overall, the usual diet was associated with weight gain, p = 0.002. Antidepressants (75%) and benzodiazepines (72%) were prevalent; these drugs were associated with weight gain, p = 0.01; 80% pts did not practice any physical activity.

Conclusions

There was a positive association with overweight/obesity: a striking & clinically worrying prevalence of high fat mass, abdominal fat, weight gain, poor nutritional intake and sedentarism. This unhealthy pattern points towards the need of a multidisciplinary approach to promote healthy lifestyles that may help depressive disorder management.

【 授权许可】

   
2014 Correia and Ravasco; licensee BioMed Central.

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