Cryptosporidium cuniculus - new records in human and kangaroo in Australia

Particle and Fibre Toxicology

Robin B Gasser³  Shane R Haydon¹  Margaret J Whipp²  Anson V Koehler³ 

[1] Melbourne Water Corporation, Docklands 3008, Victoria, Australia;Microbiological Diagnostic Unit, Public Health Laboratory, Doherty Institute, The University of Melbourne, Parkville 3010, Victoria, Australia;Faculty of Veterinary and Agricultural Science, The University of Melbourne, Parkville 3010, Victoria, Australia

关键词: Novel genotype;    Kangaroo;    Human;    Australia;    Cryptosporidium cuniculus;   

Others  :  1149497
DOI  :  10.1186/s13071-014-0492-8

 received in 2014-09-02, accepted in 2014-10-20,  发布年份 2014

【 摘 要 】

Background

To date, Cryptosporidium cuniculus has been found exclusively in rabbits and humans. The present study provides the first published molecular evidence for C. cuniculus in an Australian human patient as well as a kangaroo.

Findings

Using PCR-based sequencing of regions in the actin, 60 kDa glycoprotein (gp60) and small subunit of ribosomal RNA (SSU) genes, we identified a new and unique C. cuniculus genotype (akin to VbA25) from a human, and C. cuniculus genotype VbA26 from an Eastern grey kangaroo (Macropus giganteus) in Australia.

Conclusions

The characterisation of these genotypes raises questions as to their potential to infect humans and/or other animals in Australia, given that C. cuniculus has been reported to cause cryptosporidiosis outbreaks in Europe.

【 授权许可】

   
2014 Koehler et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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