Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation

Reproductive Health

Geraldine Emerson²  Simona Cumpata²  Radu Maftei²  Gabriela Simionescu²  Mihaela Zlei¹  Bogdan Doroftei² 

[1] Laboratory of Molecular Biology, Regional Institute of Oncology, Romania, 2-4 Berthelot Street, Iasi, postal code 700483, Romania;Origyn Fertility Center, Iasi, Romania

关键词: IMSI;    Artificial Oocyte Activation;    Globozoospermia;   

Others  :  1210307
DOI  :  10.1186/s12978-015-0031-x

 received in 2014-11-20, accepted in 2015-04-29,  发布年份 2015

【 摘 要 】

We report a successful ongoing pregnancy obtained in a case of total globozoospermia after intracytoplasmic morphologically selected sperm injection (IMSI) with oocyte activation. The first semen analysis on investigation showed partial globozoospermia. However, under high magnification assessment at oocyte retrieval only round headed sperm were observed. Considering the high risk of a complete failure to fertilize from IMSI the couple gave written informed consent to the use of oocyte activation media post IMSI. One embryo fertilized, developed to a hatching blastocyst and was transferred resulting in an ongoing pregnancy. This successful outcome shows the use of IMSI is useful in the evaluation of total globozooozpermia and therefore aids in the justification of the use of oocyte activation media.

【 授权许可】

   
2015 Doroftei et al.; licensee BioMed Central.

【 图 表 】

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