Metastatic sweat gland adenocarcinoma: A clinico-pathological dilemma

World Journal of Surgical Oncology

Anju Bansal¹  Sunita Saxena¹  Vinay Singhal²  Rohini Badran²  RD Sharma²  Chintamani² 

[1] Institute of Pathology, Indian Council of Medical Research (ICMR), New Delhi 110023 India;Department of Surgery, Vardhman Mahavir Medical College & Safdarjang Hospital, New Delhi 110023 India

关键词: metastasis;    lymph node;    eccrine;    apocrine;    adenocarcinoma;    Sweat gland;   

Others  :  1207508
DOI  :  10.1186/1477-7819-1-13

 received in 2003-01-19, accepted in 2003-08-01,  发布年份 2003

【 摘 要 】

Background

Sweat gland adenocarcinoma is a rare malignancy with high metastatic potential seen more commonly in later years of life. Scalp is the most common site of occurrence and it usually spreads to lymph nodes. Liver, lung and bones are the distant sites of metastasis with fatal results. The differentiation between apocrine and eccrine metastatic sweat gland carcinoma is often difficult. The criteria's are inadequate to be of any practical utility.

Case Report

Two cases of metastatic sweat gland adenocarcinoma (one of eccrine and the other one of apocrine origin) are being reported on account of the rarity and different outcome.

Conclusion

Sweat gland carcinomas are rare cancers with a poor prognosis often presenting as histological surprises. Surgery in the form of wide local excision and lymph node dissection is the mainstay of treatment. Chemotherapy and/or radiotherapy has limited role.

【 授权许可】

   
2003 Chintamani et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

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