Postoperative recurrence of desmoid tumors: clinical and pathological perspectives

World Journal of Surgical Oncology

Shun Tang²  Tao Ji²  Xiao-dong Tang²  Rong-li Yang²  Kun-kun Sun¹  Wei Guo²  Yi-fei Wang² 

[1] Department of Pathology, Peking University People’s Hospital, Beijing 100044, P.R. China;Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing 100044, P.R. China

关键词: Tumor resection;    Immunohistochemistry;    Histopathology;   

Others  :  1146278
DOI  :  10.1186/s12957-015-0450-8

 received in 2014-06-13, accepted in 2015-01-08,  发布年份 2015

【 摘 要 】

Background

The clinical features and the pathological changes of desmoid tumors were studied to point out the key factors affecting the recurrence.

Methods

The clinical data and specimens of 56 patients who underwent desmoid tumor resection from 2003 to 2008 were reviewed. Possible clinical factors related to the postoperative recurrence were analyzed statistically. The specimens round the lesions were studied histopathologically.

Results

The overall recurrence rate was 39.3%. The postoperative recurrence rate of the patients with negative surgical margins and no tumor invasion of the major vessels and nerves was low (P < 0.05). However, the desmoid tumors could destroy the cortical bone and invade the medullary cavity.

Conclusions

Desmoid tumors were pathologically benign, which could extensively invade tissues around the lesions. The invasion of major vessels and nerves and quality of surgical margins are the key factors for the high postoperative recurrence rate.

【 授权许可】

   
2015 Wang et al.; licensee BioMed Central.

【 图 表 】

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