BetaHCG secretion by a pulmonary adenocarcinoma

World Journal of Surgical Oncology

Anne Madroszyk³  Patrice Viens¹  Bruno Chetaille²  Anthony Gonçalves¹  Agnès Tallet⁴  Emeline Tabouret¹  Cécile Vicier¹ 

[1]Aix-Marseille Université, 13001 Marseille, France

[2]Institut Paoli-Calmettes, Anatomopathology, 13009 Marseille, France

[3]Department of Medical Oncology, Institut Paoli-Calmettes, 13009 Marseille, France

[4]Radiotherapy Department, Institut Paoli-Calmettes, 13009 Marseille, France

关键词: Ectopic pregnancy;    Paraneoplastic syndromes;    Non-small-cell lung cancer;    BetaHCG;   

Others  :  822082
DOI  :  10.1186/1477-7819-11-228

 received in 2013-04-24, accepted in 2013-09-11,  发布年份 2013

【 摘 要 】

We report a rare case of metastatic non-small-cell lung cancer in a 43-year-old woman with a history of smoking. The tumor secreted human chorionic gonadotropin and its beta subunit (BetaHCG). The patient presented with amenorrhea, a positive pregnancy test and chest pain. A physical examination and investigations revealed no pregnancy, and it was determined that a paraneoplastic syndrome stemming from a pulmonary tumor was responsible for the secretion of BetaHCG. This secretion decreased with tumor response to chemotherapy. Only a few reports of paraneoplastic BetaHCG secretion can be found in the literature for several different cancers.

【 授权许可】

   
2013 Vicier et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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