Potential biomarkers for predicting outcomes in CABG cardiothoracic surgeries

Journal of Cardiothoracic Surgery

K Stephen Suh³  Elie Elman¹  Leonard Y Lee²  Ahmed Abdel-Razek¹  Kyung Hwa Jeong³  Rajendra Gharbaran³  Isabel Preeshagul³ 

[1] Cardiothoracic Surgery Division, Hackensack University Medical Center, Hackensack NJ 07601NJ, USA;Division of Cardiothoracic Surgery, UMDNJ-Robert Wood Johnson Medical School, New Brunswick 08901NJ, USA;The John Theurer Cancer Center, Hackensack University Medical Center, Hackensack NJ 07601, NJ, USA

关键词: Predictive markers;    Serum;    Clinical outcome;    Cardiothoracic surgery;    Biomarker;   

Others  :  824238
DOI  :  10.1186/1749-8090-8-176

 received in 2012-09-10, accepted in 2013-06-06,  发布年份 2013

【 摘 要 】

The variations in recovery time, complications, and survival among cardiac patients who have undergone coronary artery bypass graft (CABG) procedures are vast. Many formulas and theories are used to predict clinical outcome and recovery time, and current prognostic predictions are based on medical and family history, lifestyle, co-morbidities, and performance status. The identification of biomarkers that provide concrete evidence supporting clinical outcome has greatly affected the field of medicine, helping clinicians in many medicine sub-specialties to forecast clinical course. Recent studies have discovered biomarkers that may be used as predictors of cardiac patients’ status post-cardiothoracic surgery, and the applications are numerous. In this review, we assess currently available cardiac biomarkers as predictors of clinical outcome for post-operative CABG patients. Data were collected from various studies in which cardiac biomarkers were measured in pre-operative and post-operative CABG patients.

【 授权许可】

   
2013 Preeshagul et al.; licensee BioMed Central Ltd.

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