Traumatic injury among females: does gender matter?

Journal of Trauma Management & Outcomes

Rifat Latifi³  Ruben Peralta²  Ashok Parchani²  Ahmad Zarour²  Husham Abdelrahman²  Mohammad Asim⁴  Hassan Al-Thani²  Hany El-Hennawy²  Ayman El-Menyar¹ 

[1] Internal Medicine, Ahmed Maher Teaching Hospital, Cairo, Egypt;Trauma Surgery Section, Hamad General Hospital, Doha, Qatar;Department of Surgery, Arizona University, Tucson, AZ, USA;Clinical Research, Trauma Surgery Section, Hamad General Hospital, PO Box 3050, Doha, Qatar

关键词: Female;    Injury mechanisms;    Gender;    Trauma;   

Others  :  1133132
DOI  :  10.1186/1752-2897-8-8

 received in 2014-03-11, accepted in 2014-07-22,  发布年份 2014

【 摘 要 】

Background

Trauma remains one of the leading causes of morbidity and mortality worldwide. Generally, the incidence of traumatic injuries is disproportionately high in males. However, trauma in females is underreported.

Aim

To study the epidemiology and outcome of different mechanisms and types of traumatic injuries in women.

Methods

We conducted a traditional narrative review using PubMed, MEDLINE and EMBASE, searching for English-language publications for gender-specific trauma between January 1993 and January 2013 using key words “trauma”, “gender”, “female” and “women”.

Results

Among 1150 retrieved articles, 71 articles were relevant over 20 years. Although it is an important public health problem, traumatic injuries among females remain under-reported.

Conclusion

There is a need for further research and evaluation of the exact burden of traumatic injuries among females together with the implementation of effective community based preventive programs.

【 授权许可】

   
2014 El-Menyar et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

【 参考文献 】

• [1]Centers for Disease Control and Prevention, National Center for Injury Prevention and Control: Web–based Injury Statistics Query and Reporting System (WISQARS) [online]. Atlanta, GA; Retrieved from http://www.cdc.gov/injury/wisqars/ webcite Accessed April 11, 2012
• [2]Torpy JM: Burn injuries. JAMA 2009, 302(16):1828. http://www.jama.jamanetwork.com/article.aspx?articleid=18478643 webcite. Road traffic injuries, WHO Fact sheet N°358, March 2013. http://www.who.int/mediacentre/factsheets/fs358/en/ webcite, last access 24/03/2013
• [3]Bener A, Zirie MA, Kim EJ, Al Buz R, Zaza M, Al-Nufal M, Basha B, Hillhouse EW, Riboli E: Measuring burden of diseases in a rapidly developing economy: state of Qatar. Glob J Health Sci 2012, 5(2):134-144.
• [4]Makama JG, Garba ES, Ameh EA: Under representation of women in surgery in Nigeria: by choice or by design? Oman Med J 2012, 27(1):66-69.
• [5]Hoel AW, Kayssi A, Brahmanandam S, Belkin M, Conte MS, Nguyen LL: Under-representation of women and ethnic minorities in vascular surgery randomized controlled trials. J Vasc Surg 2009, 50(2):349-354.
• [6]Jagsi R, Motomura AR, Amarnath S, Jankovic A, Sheets N, Ubel PA: Under-representation of women in high-impact published clinical cancer research. Cancer 2009, 115(14):3293-3301.
• [7]El-Menyar A, Latifi R, AbdulRahman H, Zarour A, Tuma M, Parchani A, Peralta R, al Thani H: Age and traumatic chest injury: a 3-year observational study. Eur J Trauma Emerg Surg 2013. doi:10.1007/s00068-013-0281-7
• [8]Abdulrahman H, Afifi I, El-Menyar A, Al-Hassani A, Almadani A, Al-Thani H, Latifi R: Clinical outcomes of multiple rib fractures: does age matter? Eur J Trauma Emerg Surg 2013, 39:605-611. doi:10.1007/s00068-013-0291-5
• [9]El-Menyar A, AbdulRahman H, al Thani H, Zarour A, Tuma M, Parchani A, Peralta R, Latifi R: Traumatic Blunt Abdominal Injury from the anatomical piont of view. Lyon, France: Presented at 14th Eur Cong Trauma & Emerg Surg; 2013.
• [10]El-Faramawy A, El-Menyar A, Zarour A, Maull K, Riebe J, Kumar K, Mathew J, Parchani A, Al-Thani H, Latifi R: Presentation and outcome of traumatic spinal fractures. J Emerg Trauma Shock 2012, 5(4):316-320.
• [11]El-Matbouly M, El-Menyar A, Al-Thani H, Tuma M, El-Hennawy H, Abdulrahman H, Parchani A, Peralta R, Asim M, El-Faramawy A, Zarour A, Latifi R: Traumatic brain injury in qatar: age matters- insights from A 4-year observational study. Scientific World Journal 2013doi:10.1155/2013/354920
• [12]Abdulrazzaq H, Zarour A, El-Menyar A, Majid M, Al Thani H, Asim M, Latifi R, Maull K: Pedestrians: the daily underestimated victims on the road. Int J Inj Contr Saf Promot 2012. [Epub ahead of print] PubMed PMID: 23194603
• [13]Zarour A, El-Menyar A, Al-Thani H, Scalea TM, Chiu WC: Presentations and outcomes in patients with traumatic diaphragmatic injury: a 15-year experience. J Trauma Acute Care Surg 2013, 74(6):1392-1398.
• [14]Tuma MA, Acerra JR, El-Menyar A, Al-Thani H, Al-Hassani A, Recicar JF, Al Yazeedi W, Maull KI: Epidemiology of workplace-related fall from Height and cost of trauma care in Qatar. Int J Crit Illn Inj Sci 2013, 3(1):3-7.
• [15]Atique S, Zarour A, Siddiqui T, El-Menyar A, Maull K, Al Thani H, Latifi R: Trauma caused by falling objects at construction sites. J Trauma Acute Care Surg 2012, 73(3):704-708.
• [16]Latifi R, El-Menyar A, Al-Thani H, Zarour A, Parchani A, Abdulrahman H, Asim M, Peralta R, Consunji R: Cultural aspect of pedestrian injuries amongst expat workers in Qatar: An opportunity for an injury prevention program. Qatar Foundation Annual Research Forum Proceedings. Vol. 2012, BMP74. doi:10.5339/qfarf.2012.BMP74
• [17]El-Menyar A, Zubaid M, Rashed W, Almahmeed W, Al-Lawati J, Sulaiman K, Al-Motarreb A, Amin H, R S, Al Suwaidi J: Comparison of men and women with acute coronary syndrome in six Middle Eastern countries. Am J Cardiol 2009, 104(8):1018-1022.
• [18]Al-Thani HA, El-Menyar A, Zubaid M, Rashed WA, Ridha M, Almahmeed W, Sulaiman K, Al-Motarreb A, Amin H, Al Suwaidi J: Peripheral arterial disease in patients presenting with acute coronary syndrome in six middle eastern countries. Int J Vasc Med 2011, 2011:815902. doi:10.1155/2011/815902
• [19]Road traffic injuries, WHO Fact sheet N°358, March 2013. http://www.who.int/mediacentre/factsheets/fs358/en/ webcite, last access 24/03/2013
• [20]Northern Ireland Statistics and Research Agency (NISRA): 2009 Mid-year population estimates. 2010. http://www.nisra.gov.uk/demography/default.asp17.htm webcite
• [21]Office for National Statistics (ONS): Mortality statistics Deaths registered in 2009 Tables 1 and 5.19. 2010. http://www.statistics.gov.uk/downloads/theme_health/dr2009/dr-09.pdf webcite
• [22]World Health Organization: Gender and Road Traffic Injuries. 2002. http://www.who.int/gender/other_health/en/gendertraffic.pdf webcite. last access 24/03/2013
• [23]WHO FALL Fact sheet N°344, October 2012. http://www.who.int/mediacentre/factsheets/fs344/en/ webcite last access 24/03/2013
• [24]WHO, D.o.I.a.V.P: Noncommunicable Disease and Mental Health Cluster, The Injury Chart Book. Fall-related injuries. Geneva, Switzerland: World Health Organization; 2002.
• [25]Yoshida S: A Global Report on Falls Prevention Epidemiology of Falls. http://www.who.int/ageing/projects/1.Epidemiology%20of%20falls%20in%20older%20age.pdf webcite
• [26]Morrison A, Fan T, Sen SS, Weisenfluh L: Epidemiology of falls and osteoporotic fractures: a systematic review. Clinicoecon Outcomes Res 2013, 5:9-18.
• [27]Kantayaporn C: Fall with and without fracture in elderly: what’s different? J Med Assoc Thai 2012, 95(Suppl 10):S109-S112.
• [28]Donald IP, Bulpitt CJ: The prognosis of falls in elderly people living at home. Age Ageing 1999, 28:121-125.
• [29]Stevens JA, Sogolow ED: Gender differences for non-fatal unintentional fall related injuries among older adults. Inj Prev 2005, 11:115-119.
• [30]National Hospital Discharge Survey (NHDS): National Center for Health Statistics. Available at: http://www.cdc.gov/nchs/hdi.htm webcite. Assessed September 14, 2011
• [31]Sophonratanapokin B, Sawangdee Y, Soonthorndhada K: Effect of the living environment on falls among the elderly in Thailand. Southeast Asian J Trop Med Public Health 2012, 43(6):1537-1547.
• [32]Stevens JA, Dellinger AM: Motor vehicle and fall related deaths among older Americans 1990–98: sex, race, and ethnic disparities. Inj Prev 2002, 8:272-275.
• [33]World Health Organization: The Global Burden of Disease: 2004 Update. Geneva: World Health Organization; 2008. http://www.who.int/healthinfo/global_burden_disease/GBD_report_2004update_full.pdf webcite (Accessed on April 02, 2010)
• [34]Attia AF, Sherif AA, Mandil AM, Massoud MN, Abou-Nazel MW, Arafa MA: Epidemiological and sociocultural study of burn patients in Alexandria, Egypt. East Mediterr Health J 1997, 3(3):452-461.
• [35]Groohi B, Alaghehbandan R, Lari AR: Analysis of 1089 burn patients in province of Kurdistan. Iran Burns 2002, 28(6):569-574.
• [36]Estahbanati HK, Kashani PP, Ghanaatpisheh F: Frequency of Pseudomonas aeruginosa serotypes in burn wound infections and their resistance to antibiotics. Burns 2002, 28(4):340-348.
• [37]Lawrence JW, Mason ST, Schomer K, Klein MB: Epidemiology and impact of scarring after burn injury: a systematic review of the literature. J Burn Care Res 2012, 33(1):136-146.
• [38]Jeschke MG, Mlcak RP, Finnerty CC, Norbury WB, Przkora R, Kulp GA, Gauglitz GG, Zhang XJ, Herndon DN: Gender differences in pediatric burn patients: does it make a difference? Ann Surg 2008, 248(1):126-136.
• [39]Jeschke MG, Przkora R, Suman OE, Finnerty CC, Mlcak RP, Pereira CT, Sanford AP, Herndon DN: Sex differences in the long-term outcome after a severe thermal injury. Shock 2007, 27(5):461-465.
• [40]Kerby JD, McGwin G Jr, George RL, Cross JA, Chaudry IH, Rue LW 3rd: Sex differences in mortality after burn injury: results of analysis of the national burn repository of the American burn association. J Burn Care Res 2006, 27(4):452-456.
• [41]Barrow RE, Przkora R, Hawkins HK, Barrow LN, Jeschke MG, Herndon DN: Mortality related to gender, age, sepsis, and ethnicity in severely burned children. Burns 2005, 23:485-487.
• [42]Kobayashi K, Ikeda H, Higuchi R, Nozaki M, Yamamoto Y, Urabe M, Shimazaki S, Sugamata A, Aikawa N, Ninomiya N, Sakurai H, Hamabe Y, Yahagi N, Nakazawa H: Epidemiological and outcome characteristics of major burns in Tokyo. Burns 2005, 31(Suppl 1):S3-S11.
• [43]McGwin G Jr, George RL, Cross JM, Reiff DA, Chaudry IH, Rue LW 3rd: Gender differences in mortality following burn injury. Shock 2002, 18(4):311-315.
• [44]John PR, Shiozawa A, Haut ER, Efron DT, Haider A, Cornwell EE 3rd, Chang D: An assessment of the impact of pregnancy on trauma mortality. Surgery 2011, 149(1):94-98.
• [45]Mighty H: Trauma in pregnancy. Crit Care Clin 1994, 10:623-634.
• [46]Peckham CH, King RA: A study of intercurrent conditions observed during pregnancy. Am J Obstet Gynecol 1963, 87:609-624.
• [47]Lavin JP, Polsky SS: Abdominal trauma during pregnancy. Clin Perinatol 1983, 10:423-438.
• [48]Esposito TJ: Trauma during pregnancy. Emerg Med Clin North Am 1994, 12:167-199.
• [49]Nash P, Driscoll P: ABC of major trauma: trauma in pregnancy. BMJ 1990, 301:974-976.
• [50]Mendez-Figueroa H, Dahlke JD, Vrees RA, Rouse DJ: Trauma in pregnancy: an updated systematic review. Am J Obstet Gynecol 2013. doi:0.1016/j.ajog.2013.01.021
• [51]Shah KH, Simons RK, Holbrook T, Fortlage D, Winchell RJ, Hoyt DB: Trauma in pregnancy: maternal and fetal outcomes. J Trauma 1998, 45(1):83-86.
• [52]George ER, Vanderkwaak T, Scholten DJ: Factors influencing pregnancy outcome after trauma. Am Surg 1992, 58:594-598.
• [53]Dahmus MA, Sibai BM: Blunt abdominal trauma: are there any predictive factors for abruptio placentae or maternal-fetal distress? Am J Obstet Gynecol 1993, 169:1054-1059.
• [54]Kettel LM, Branch DW, Scott JR: Occult placental abruption after maternal trauma. Obstet Gynecol 1988, 71:449-453.
• [55]El-Kady D, Gilbert WM, Anderson J, Danielsen B, Towner D, Smith LH: Trauma during pregnancy: an analysis of maternal and fetal outcomes in a large population. Am J Obstet Gynecol 2004, 190(6):1661-1668.
• [56]Scorpio RJ, Esposito TJ, Smith LG, Gens DR: Blunt trauma during pregnancy: factors affecting fetal outcome. J Trauma 1992, 32(2):213-216.
• [57]Chu I, Vaca F, Stratton S, Chakravarthy B, Hoonpongsimano , Lotfipour S: Geriatric trauma care: challenges facing emergency medical services. Cal J Emerg Med 2007, VIII(2 May):51-55.
• [58]Melton LJ 3rd, Chrischilles EA, Cooper C, Lane AW, Riggs BL: How many women have osteoporosis? J Bone Min Res 1992, 7:1005-1010.
• [59]Marks R, Allegrante JP, Ronald MacKenzie C, Lane JM: Hip fractures among the elderly: causes, consequences and control. Ageing Res Rev 2003, 2:57-93.
• [60]Gerald McGwin MS, May AK, Melton SM, Reiff DA, Rue LW: Recurrent trauma in elderly patients. Arch Surg 2001, 136(2):197-203.
• [61]The Crash Outcome Data Evaluation System (CODES), U.S. Department of Transportation, National Highway Traffic Safety Administration 1996. http://www.nhtsa.gov/people/injury/research/connecticut/evalofelderlydrv.html webcite
• [62]The prevention and management of fragility fractures in northern Ireland: Report of the fragility fracture working group (June 2009). http://www.nos.org.uk/netcommunity/document.doc?id=529 webcite. Last accessed 6 June 2014
• [63]Osteoporosis: assessing the risk of fragility fracture. 2012. http://www.nice.org.uk/nicemedia/live/13857/60399/60399.pdf webcite. Last accessed 6 June 2014
• [64]Quansah B, Stammers J, Sivapathasuntharam D, Culpan P, Bates P: Fragility fractures of the pelvis in the elderly population. Hard Tissue 2013, 2(1):2.
• [65]Cassell E, Ozanne-Smith J: Women’s Injury In The Home. Monash University Accident Research Centre. 1999. http://www.monash.edu.au/miri/research/reports/muarc158.html webcite. Accessed at 25 April 2013
• [66]Deitch EA, Livingston DH, Lavery RF, Monaghan SF, Bongu A, Machiedo GW: Hormonally active women tolerate shock-trauma better than do men. Ann Surg 2007, 246:447-455.
• [67]Ottochian M, Salim A, Berry C, Chan LS, Wilson MT, Margulies DR: Severe traumatic brain injury: is there a gender difference in mortality? Am J Surg 2009, 197:155-158.
• [68]Napolitano LM, Greco ME, Rodriguez A, Kufera JA, West RS, Scalea TM: Gender differences in adverse outcomes after blunt trauma. J Trauma 2001, 50:274-280.
• [69]Hsieh YC, Frink M, Choudhry MA, Bland KI, Chaudry IH: Metabolic modulators following trauma sepsis: Sex hormones. Crit Care Med 2007, 35:S621-S629.
• [70]Knöferl MW, Diodato MD, Angele MK, Ayala A, Cioffi WG, Bland KI, Chaudry IH: Do female sex steroids adversely or beneficially affect the depressed immune responses in males after trauma-hemorrhage? Arch Surg 2000, 135:425-433.
• [71]Llompart-Pou J, Raurich J, Al Ibanez J: Relationship between plasma adrenocorticotropin hormone and intensive care unit survival in early traumatic brain injury. J Trauma Inj Infect Crit Care 2007, 62:1457-1461.
• [72]Choudhry MA, Bland KI, Chaudry IH: Gender and susceptibility to sepsis following trauma. Endocr Metab Immune Disord Drug Targets 2006, 6(2):127-135.
• [73]Houston-Bolze MS, Downing MT, Sayed AM, Meserve LA: Gender differences in the responses of serum insulin-like growth factor-1 and transthyretin (prealbumin) to trauma. Crit Care Med 1996, 24(12):1982-1987.
• [74]Ertan T, Keskek M, Kilic M, Gocmen E, Oguz H, Aksaray S, Koc M: Effects of gender difference in early cytokine levels in trauma patients. Bratisl Lek Listy 2007, 108(3):128-132.
• [75]Jeschke MG, Barrow RE, Mlcak RP, Herndon DN: Endogenous anabolic hormones and hypermetabolism: effect of trauma and gender differences. Ann Surg 2005, 24(5):759-767.
• [76]Mohr AM, Lavery RF, Sifri ZC, Anjaria DJ, Koernig R, Eitch EA, Livingston DH: Am Gender differences in glucose variability after severe trauma. Surg 2010, 76(8):896-902.
• [77]Horton JW, White DJ, Maass DL: Gender-related differences in myocardial inflammatory and contractile responses to major burn trauma. Am J Physiol Heart Circ Physiol 2004, 286:H202-H213.
• [78]Choudhry MA, Bland KI, Chaudry IH: Trauma and immune response – effect of gender differences. Injury 2007, 38(12):1382-1391.
• [79]Plackett TP, Gamelli RL, Kovacs EJ: Gender-based differences in cytokine production after burn injury: a role of interleukin-6. J Am Coll Surg 2010, 210:73-78.
• [80]Mostafa G, Huynh T, Sing RF, Miles WS, Norton HJ: Thomason MH - Gender-related outcomes in trauma. J Trauma 2002, 53(3):430-434.
• [81]George RL, McGwin G, Metzger J, Chaudry IH, Rue LW: The association between gender and mortality among trauma patients as modified by age. J Trauma 2003, 54(3):464-471.
• [82]Rappold JF, Coimbra R, Hoyt DB, Potenza BM, Fortlage D, Holbrook T, Minard G: Female gender does not protect blunt trauma patients from complications and mortality. J Trauma 2002, 53(3):436-441.
• [83]O’Keefe GE, Hunt JL: Purdue GF - An evaluation of risk factors for mortality after burn trauma and the identification of gender-dependent differences in outcomes. J Am Coll Surg 2001, 192(2):153-160.
• [84]Hannan EL, Mendeloff J, Farrell LS, Cayten CG: Murphy JG - Multivariate models for predicting survival of patients with trauma from low falls: the impact of gender and pre-existing conditions. J Trauma 1995, 38(5):697-704.
• [85]Kraus JF, Peek-Asa C, McArthur D: The independent effect of gender on outcomes following traumatic brain injury: a preliminary investigation. Neurosurg Focus 2000, 15(8(1)):e5.
• [86]Farace E, Alves WM: Do women fare worse? A metaanalysis of gender differences in outcome after traumatic brain injury. Neurosurg Focus 2000, 8(1):e6.
• [87]Leitgeb J, Mauritz W, Brazinova A, Janciak I, Majdan M, Wilbacher I, Rusnak M: Effects of gender on outcomes after traumatic brain injury. J Trauma 2011, 71(6):1620-1626.
• [88]Yu AH, Cheng CH, Yeung JH, Poon WS, Ho H, Chang A, Rainer TH: Functional outcome after head injury: comparison of 12-45 year old male and female hormonally active patients. Injury 2012, 43(5):603-607.
• [89]Ytterstad B: The Harstad injury prevention study: community based prevention of fall-fractures in the elderly evaluated by means of a hospital based injury recording system in Norway. J Epidemiol Community Health 1996, 50:551-558.
• [90]Rodrigues J, Ciosak SI: Elderly victims of trauma: analysis of the risk factors. Rev Esc Enferm USP 2012, 46(6):1400-1405.
• [91]Dandona R, Kumar GA, Raj TS, Dandona L: Patterns of road traffic injuries in a vulnerable population in Hyderabad. India Inj Prev 2006, 12(3):183-188.