Confirmation of quantitative trait loci affecting fatness in chickens

Genetics Selection Evolution

Martien AM Groenen¹  Jan J van der Poel¹  Richard MPA Crooijmans¹  Henk Bovenhuis¹  Addie LJ Vereijken²  Danyel GJ Jennen³ 

[1] Animal Breeding and Genetics Group, Wageningen Institute of Animal Sciences, Wageningen University, Marijkeweg 40, 6709 PG Wageningen, The Netherlands;Nutreco, Breeding Research Centre, P.O. Box 220, 5830 AE Boxmeer, The Netherlands;Institute of Animal Breeding Science, University Bonn, Endenicher Allee 15, 53113 Bonn, Germany

关键词: fatness traits;    chicken;    advanced intercross line;    quantitative trait loci;   

Others  :  1094244
DOI  :  10.1186/1297-9686-37-3-215

 received in 2003-09-08, accepted in 2004-08-16,  发布年份 2005

【 摘 要 】

In this report we describe the analysis of an advanced intercross line (AIL) to confirm the quantitative trait locus (QTL) regions found for fatness traits in a previous study. QTL analysis was performed on chromosomes 1, 3, 4, 15, 18, and 27. The AIL was created by random intercrossing in each generation from generation 2 (G₂) onwards until generation 9 (G₉) was reached. QTL for abdominal fat weight (AFW) and/or percentage abdominal fat (AF%) on chromosomes 1, 3 and 27 were confirmed in the G₉ population. In addition, evidence for QTL for body weight at the age of 5 (BW5) and 7 (BW7) weeks and for the percentage of intramuscular fat (IF%) were found on chromosomes 1, 3, 15, and 27. Significant evidence for QTL was detected on chromosome 1 for BW5 and BW7. Suggestive evidence was found on chromosome 1 for AFW, AF% and IF%, on chromosome 15 for BW5, and on chromosome 27 for AF% and IF%. Furthermore, evidence on the chromosome-wise level was found on chromosome 3 for AFW, AF%, and BW7 and on chromosome 27 for BW5. For chromosomes 4 and 18, test statistics did not exceed the significance threshold.

【 授权许可】

   
2005 INRA, EDP Sciences