Low prevalence of Neospora caninum and Toxoplasma gondii antibodies in dogs in Jilin, Henan and Anhui Provinces of the People’s Republic of China

BMC Veterinary Research

Jitender Prakash Dubey¹  Hongde Liang²  Oliver Chun Hung Kwok¹  Yuqing Ying¹  Yangguang Kong²  Qiongfang Zhang²  Yurong Yang¹ 

[1] United States Department of Agriculture, Agricultural Research Service, Beltsville Agricultural Research Center, Animal Parasitic Diseases Laboratory, Beltsville 20705-2350, MD, USA;Laboratory of Veterinary Pathology, College of Animal Science and Veterinary Medicine, Henan Agriculture University, Zhengzhou 450002, PR China

关键词: Neospora agglutination test;    Modified agglutination test;    China;    Dogs;    Seroepidemiology;    Toxoplasma gondii;    Neospora caninum;   

Others  :  1091816
DOI  :  10.1186/s12917-014-0295-3

 received in 2014-09-07, accepted in 2014-12-05,  发布年份 2014

【 摘 要 】

Background

Neospora caninum and Toxoplasma gondii are important pathogens of worldwide distribution. N. caninum is a major cause of abortion in cattle and dogs are main reservoirs because they excrete the environmentally resistant oocysts. Toxoplasmosis is a worldwide zoonosis and dogs are considered as sentinels for this parasite because of their close contact with people and cats; additionally dog meat is also used for human consumption in China. The aim of the present study was to assess the prevalence of N. caninum and T. gondii infection in dogs from China. A total of 425 countryside dog hearts in Jilin, Henan and Anhui provinces of the People’s Republic of China were collected from slaughter houses in two batches; the first batch of 96 in October 2013, and the second batch of 329 in April 2014. Serum samples extracted from 96 dog hearts were tested for antibodies to N. caninum and from 425 dog hearts were tested for T. gondii antibodies in the modified agglutination tests (cut-off 1:25 for both), using respective antigens.

Results

Antibodies to N. caninum were 6 of 96 (6.25%) of dogs with titers of 1:25 in 2, 1:50 in 3, and 1:100 in 1. All seropositive dogs were more than 1 year old. Antibodies to T. gondii were found in 35 of 425 (8.24%) dogs with titers of 1:25 in 15, 1:50 in 14; and 1:100 in 6.

Conclusion

The results of the present study indicated low prevalence of N. caninum and T. gondii antibodies in dogs of China, compared with Europe and America. Identification of the risk factors that underlie these differences may help prevention of neosporosis and toxoplasmosis. This is the first report of N. caninum infection in dogs from China.

【 授权许可】

   
2014 Yang et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

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