期刊论文详细信息
Journal of Cardiothoracic Surgery
Contemporary outcomes of open repair of thoracoabdominal aortic aneurysm in young patients
Roderick TA Chalmers1  Paul J Burns1  Orwa Falah1  Alastair F Nimmo1  Carl Moores1  Carlo Ceresa1  Russell W Jamieson1  Neil Johns1 
[1] Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh EH16 4SB, UK
关键词: Young;    Aneurysm;    Aorta;    Thoracoabdominal;   
Others  :  1136112
DOI  :  10.1186/s13019-014-0195-4
 received in 2014-08-18, accepted in 2014-12-04,  发布年份 2014
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【 摘 要 】

Background

Endovascular technology now permits total endovascular thoracoabdominal aortic aneurysm (TAAA) repair with high volume centres reporting encouraging results. The long-term durability of such stent grafts is unknown, leading to concerns regarding their use in younger patients. This study reports contemporary outcomes of open repair in young patients.

Methods

Outcomes for patients age 60 or younger undergoing open TAAA repair between June 1999 and August 2013 with prospective collected data were analysed retrospectively.

Results

Thirty-seven patients (31 men, 84%) with a median age of 56 (range 22–60) were identified with a median TAAA diameter of 6.9 cm (range 5.6-11). Aneurysm aetiology included degenerative change (18), dilation of chronic dissection (10), connective tissue disease (7) and mycotic degeneration (2). Crawford Type IV TAAA were most commonly treated (17), followed by Type II (10), Type III (7) and Type I (3). Two (5%) patients died in hospital, one from multiple organ failure and one from respiratory failure. Three patients (8%) developed temporary paraplegia, all of whom made a complete recovery and 4 (11%) patients required temporary renal replacement therapy. Median critical care stay was 5 days (range 2–28) with an in-hospital stay of 14 days (range 7–83). During a median follow-up of 72 months (range 13–171), no patient subsequently required any further aneurysm related surgical or radiological intervention. The mean (SEM) survival time was 138.5 (11) months. The 5 year survival was 79.7% (8.3) including early deaths, with no aneurysm related complications.

Conclusions

The outcome of open TAAA repair in patients aged less than 60 years is favorable. It is against these results that evolving endovascular interventions must be compared.

【 授权许可】

   
2014 Johns et al.; licensee BioMed Central Ltd.

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