期刊论文详细信息
Genetics Selection Evolution
On the expected relationship between inbreeding, fitness, and extinction
Denis Couvet1  Konstantinos Theodorou2 
[1] CRBPO, Muséum National d'Histoire Naturelle, 55, rue Buffon, 75005 Paris, France;Biodiversity Conservation Laboratory, Department of Environmental Studies, University of the Aegean, University Hill, 81100 Mytilene, Greece
关键词: deleterious mutation;    genetic load;    conservation;    extinction;    inbreeding;   
Others  :  1094118
DOI  :  10.1186/1297-9686-38-4-371
 received in 2005-08-04, accepted in 2006-01-17,  发布年份 2006
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【 摘 要 】

We assessed the expected relationship between the level and the cost of inbreeding, measured either in terms of fitness, inbreeding depression or probability of extinction. First, we show that the assumption of frequent, slightly deleterious mutations do agree with observations and experiments, on the contrary to the assumption of few, moderately deleterious mutations. For the same inbreeding coefficient, populations can greatly differ in fitness according to the following: (i) population size; larger populations show higher fitness (ii) the history of population size; in a population that recovers after a bottleneck, higher inbreeding can lead to higher fitness and (iii) population demography; population growth rate and carrying capacity determine the relationship between inbreeding and extinction. With regards to the relationship between inbreeding depression and inbreeding coefficient, the population size that minimizes inbreeding depression depends on the level of inbreeding: inbreeding depression can even decrease when population size increases. It is therefore clear that to infer the costs of inbreeding, one must know both the history of inbreeding (e.g. past bottlenecks) and population demography.

【 授权许可】

   
2006 INRA, EDP Sciences

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