Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature

Diagnostic Pathology

Leticia Quintanilla-Martinez¹  Falko Fend¹  Zeid Bittar¹ 

[1] Institute of Pathology, University Hospital Tuebingen, Eberhard-Karls-University, Liebermeisterstrasse 8, Tuebingen 72076, Germany

关键词: Prognosis;    Microsatellite instability;    EBV;    Lymphoepithelioma-like carcinoma;   

Others  :  804015
DOI  :  10.1186/1746-1596-8-184

 received in 2013-07-30, accepted in 2013-10-26,  发布年份 2013

【 摘 要 】

A lymphoepithelioma-like carcinoma (LLC), characterized by a carcinoma with stromal heavy lymphocyte infiltration, is one of the histological patterns observed in patients with Epstein-Barr virus (EBV)-associated gastric carcinoma. Although this entity is hard to be recognized in the biopsy specimens, pathologists and clinicians should acknowledge this subset of gastric cancer because it generally has a better prognosis than other forms of EBV-associated gastric carcinomas and conventional gastric carcinomas. This might be due to the fact that the patient's inflammatory response may prevent the spread of tumor through the gastric wall and to the lymph nodes or remote organs.

We report a case of EBV-positive, microsatellite stable LLC as a rare morphologic variant of gastric carcinoma.

Virtual slides

The virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1360498724104351 webcite.

【 授权许可】

   
2013 Bittar et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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