Efficacy of an absorbable polyglycolic acid patch in surgery for pneumothorax due to silicosis

Journal of Cardiothoracic Surgery

Yi Yang¹  Chao-Xi Lin²  Chuang Chi²  Yu Liu²  Xiao-Ming Lin² 

[1] Department of Clinical Skills Center, Wenzhou Medical College, Wenzhou 325000, China;Department of Cardiac and Thoracic Surgery, the First Affiliated Hospital of Wenzhou Medical College, Wenzhou, China

关键词: Air leakage;    Pneumothorax;    Silicosis;    Polyglycolic acid patch;   

Others  :  1153360
DOI  :  10.1186/1749-8090-7-18

 received in 2012-01-02, accepted in 2012-03-06,  发布年份 2012

【 摘 要 】

Background

We conducted a retrospective study to evaluate the efficacy and safety of an absorbable polyglycolic acid (PGA) patch in surgery for refractory pneumothorax due to silicosis.

Methods

A retrospective analysis was performed of 56 patients who received thoracotomy or thoracoscopic surgery for refractory pneumothorax due to silicosis between 1995 and 2010. An absorbable PGA patch was used as a reinforcement or repair material after resection of the bulla in 24 operations and it was not used in another 32 operations. Clinical outcomes were compared between the two groups (with a PGA and without a PGA).

Results

We found that the duration of postoperative chest drainage (5.04 ± 1.12 days vs. 8.19 ± 1.60 days, p < 0.01) and hospital stay after the operation (8.33 ± 1.34 days vs. 11.56 ± 1.50 days, p < 0.01) were significantly shorter in patients who used an absorbable PGA patch in the operation compared with those who did not use a PGA patch. The incidence of initial air leakage (58.3% [14/24] vs. 93.8% [30/32], p < 0.05) and relapse rate of pneumothorax in 6 months (4% [1/24] vs. 25% [8/32], p < 0.05) were also significantly lower in patients who used an absorbable PGA patch in the operation compared with those who did not use a PGA patch. No related adverse effects of the absorbable PGA patch occurred after the operations.

Conclusions

Use of an absorbable PGA patch as a reinforcement or repair material in surgery for refractory pneumothorax due to silicosis can reduce postoperative air leakage and improve clinical outcome.

【 授权许可】

   
2012 Lin et al; licensee BioMed Central Ltd.

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