Percutaneous endoscopic gastrostomy site metastasis from head and neck squamous cell carcinoma: case series and literature review

Journal of Otolaryngology-Head & Neck Surgery

Evan R Reiter¹  James Neifeld³  Brian Kaplan²  Sasa Espino²  Alexandros Georgolios¹  Andrew T Huang¹ 

[1] Department of Otolaryngology – Head and Neck Surgery, Virginia Commonwealth University Massey Cancer Center, Richmond, VA, USA;Commonwealth University School of Medicine, Richmond, VA, USA;Department of Surgery, Virginia Commonwealth University Massey Cancer Center, Richmond, VA, USA

关键词: Prophylactic irradiation;    Metastasis;    PEG;    Head and neck cancer;    Percutaneous endoscopic gastrostomy;   

Others  :  861868
DOI  :  10.1186/1916-0216-42-20

 received in 2012-10-31, accepted in 2013-01-06,  发布年份 2013

【 摘 要 】

Objectives

To present our experience with head and neck squamous cell carcinoma (HNSCC) seeding of percutaneous endoscopic gastrostomy (PEG) sites and to review all reported cases to identify risk factors and develop strategies for complication avoidance.

Materials and methods

The records of 4 patients with PEG site metastasis from HNSCC were identified from the authors’ institution. Thirty-eight further cases were reviewed following a PubMed search and evaluation of references in pertinent articles.

Results

Review of 42 cases revealed the average time from PEG to diagnosis of metastatic disease to be 8 months. Average time to death from detection of PEG disease was 5.9 months. One-year survival following PEG metastasis was 35.5% with an overall mortality of 87.1%.

Conclusion

PEG site metastatic disease portends a poor prognosis. Early detection and aggressive therapy may provide a chance of cure. Changes in PEG technique or in timing of adjunctive therapies are possible avenues in further research to prevent this complication.

【 授权许可】

   
2013 Huang et al.; licensee BioMed Central Ltd.

【 图 表 】

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