Challenges faced by multidisplinary new investigators on addressing grand challenges in global health

Globalization and Health

Santiago Ramón-García³  Anny Fortin⁴  Helen Dimaras¹  Carmen Logie² 

[1] Division of Hematology/Oncology, SickKids Research Institute, Toronto, ON, Canada;Women’s College Research Institute, University of Toronto, Toronto, ON, Canada;Centre for Tuberculosis Research, Life Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada;Dafra Pharma Research & Development, Turnhout, Belgium

关键词: Public health professional;    Developing countries;    International cooperation;    Research;    Interdisciplinary studies;    World health;    Global health;    Public health;   

Others  :  802470
DOI  :  10.1186/1744-8603-10-27

 received in 2013-06-17, accepted in 2014-01-27,  发布年份 2014

【 摘 要 】

Background

The grand challenges approach aims to spark innovative and transformative strategies to overcome barriers to significant global health issues. Grand Challenges Canada endorses an ‘Integrated Innovation™’ approach that focuses on the intersection of scientific/technological, social and business innovation. In this article we explore themes emerging from a dialogue between the authors, who are multidisciplinary recipients of the ‘Rising Stars in Global Health’ award from Grand Challenges Canada, regarding benefits of engaging in integrated innovation research, and recommendations for how this approach may develop in the future.

Discussion

Our dialogue followed a semi-structured interview format that addressed three topics: 1) reflections on applying an Integrated Innovation™ approach for global health; 2) thoughts on participation in the Grand Challenges 2012 meeting; and 3) authors’ visions of Grand Challenges Canada and the Grand Challenge movement towards 2020. The dialogue was transcribed verbatim and we used thematic analysis techniques to identify, analyze and report themes in the data. Benefits of working using the Grand Challenges approach centered on two themes: a) the potential for scientific breakthrough and b) building interdisciplinary collaborations and a community of scholars. Challenges and opportunities for Grand Challenges in moving forward included: a) capacity building, particularly regarding Integrated Innovation™ and scale-up planning; b) interdisciplinary and international mentorship for new investigators; and c) potential for future commercialization.

Conclusions

Our discussion highlighted that Integrated Innovation™ offers the opportunity to develop new theories, methods and approaches to global health while simultaneously fostering a collaborative spirit grounded in international, interdisciplinary collaborations. However, the arguable over-emphasis on corporatization poses a major challenge for new investigators. We propose a more balanced way forward that can harness technology to foster mentorship across time and space to support the development of such skills and ideas among new investigators.

【 授权许可】

   
2014 Logie et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

【 参考文献 】

• [1]Grand Challenges in Global Health. http://www.grandchallenges.org/Explorations/Pages/Introduction.aspx webcite
• [2]World Health Organization: Grand Challenges in Genomics for Public Health in Developing Countries: Top 10 policy and research priorities to harness genomics for the greatest public health problems. 2011. http://www.who.int/rpc/grand_challenges.pdf?ua=1 webcite
• [3]Giles J: Social science lines up its biggest challenges. Nature 2011, 470:18-19.
• [4]Varmus H, Klausner R, Zerhouni E, Acharya T, Daar AS, Singer PA: Public health. Grand Challenges in Global Health. Science 2003, 302:398-399.
• [5]Singer PA, Taylor AD, Daar AS, Upshur RE, Singh JA, Lavery JV: Grand challenges in global health: the ethical, social and cultural program. PLoS Med 2007, 4:e265.
• [6]Grand Challenges Canada/Grand Défis Canada: Integrated Innovation. 2010. http://www.grandchallenges.ca/wordpress/wp-content/uploads/integratedinnovation_EN.pdf webcite
• [7]Adams J: Collaborations: The rise of research networks. Nature 2012, 490:335-336.
• [8]Walker SH, Ouellette V, Ridde V: How can PhD research contribute to the global health research agenda? Can J Public Health 2006, 97:145-148.
• [9]Berndtson K, Daid T, Tracy CS, Bhan A, Cohen ER, Upshur RE, Singh JA, Daar AS, Lavery JV, Singer PA: Grand challenges in global health: ethical, social, and cultural issues based on key informant perspectives. PLoS Med 2007, 4:e268.
• [10]Braun V, Clarke V: Using thematic analysis in psychology. Qualitative Research in Psychology 2006, 3:77-1010.
• [11]Fook J: Critical Reflectivity in Education and Practice. In Transforming Social Work Practice: Postmodern Critical Perspectives. Edited by Pease B, Fook J. St. Leonards, Sydney: Alley & Unwin; 1999:195-208.
• [12]Taylor C, White S: Practicing Reflexivity in Health and Welfare: Making Knowledge. Buckingham: Oxford University Press; 2000.
• [13]DiMasi JA, Hansen RW, Grabowski HG: The price of innovation: new estimates of drug development costs. J Health Econ 2003, 22:151-185.
• [14]Spiegel J, Labonte R, Hatcher-Roberts J, Girard J, Neufeld V on behalf of the Coalition for Global Health Research (Canada): Tackling the “10-90 gap”: a Canadian report. The Lancet 2003, 362(9387):917-918.
• [15]Doyal L: Gender and the 10/90 gap in health research. Bull World Health Organ 2004, 82(3):162.
• [16]Kilama WL: The 10/90 gap in sub-Saharan Africa: resolving inequities in health research. Acta Trop 2009, 112(Suppl 1):S8-S15.