Journal of Animal Science and Biotechnology | |
Concept and application of ideal protein for pigs | |
Jean-Yves Dourmad1  Jaap van Milgen1  | |
[1] Agrocampus Ouest, UMR1348 Pegase, Saint-Gilles 35590, France | |
关键词: Pigs; Modeling; Lactation; Ideal protein; Growth; Gestation; Amino acids; | |
Others : 1178999 DOI : 10.1186/s40104-015-0016-1 |
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received in 2014-11-10, accepted in 2015-04-03, 发布年份 2015 | |
【 摘 要 】
Knowledge about the amino acid requirements and the response of pigs to the amino acid supply is essential in feed formulation. A deficient AA supply results in a reduction in performance while an oversupply is costly and leads to excessive nitrogen excretion with a potentially negative environmental impact. Amino acid requirements are determined to a large extent by the protein deposition in the body and, for lactating sows, by the protein exported in the milk. The concept of ideal protein was developed more than 50 years ago and refers to a protein with an amino acid profile that exactly meets the animal’s requirement so that all amino acids are equally limiting for performance. Because Lys typically is the first-limiting amino acid, the ideal amino acid profile is often expressed relative to Lys. Although the ideal protein profile is often assumed to be constant for a given production stage, (small) changes in the ideal protein profile can occur within a production stage. This can be caused by changes in the relative contribution of the different components of amino acid requirements during the productive life on the animal (e.g. changes in the relative contribution of growth and maintenance). Amino acids requirements can be determined experimentally using dose–response studies. The design of the study, the chosen response criterion, and the statistical model affect the requirement estimate. Although considerable experimental work has been carried out to determine the requirements for Lys, Met, Thr, and Trp in growing pigs (and to a lesser extent in sows), little is known about the requirements for the other essential amino acids. Experimental dose–response studies generally focus on the requirement and less on the overall response (i.e. what are the consequences of an amino acid deficiency?). This latter aspect is, to some extent, accounted for in modelling approaches that quantify the response of the animal to the amino acid supply in a dynamic way. The paper describes the origin of ideal protein and illustrates how fundamental concepts of amino acid nutrition have been integrated in practical modeling approaches for the nutrition of growing pigs and sows.
【 授权许可】
2015 van Milgen and Dourmad; licensee BioMed Central.
【 预 览 】
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20150704052819942.pdf | 330KB | download | |
Figure 1. | 21KB | Image | download |
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【 参考文献 】
- [1]Wu G: Dietary requirements of synthesizable amino acids by animals: a paradigm shift in protein nutrition. J Anim Sci Biotechnol 2014, 5(1):34. BioMed Central Full Text
- [2]Mahan DC, Shields RG Jr: Essential and nonessential amino acid composition of pigs from birth to 145 kilograms of body weight, and comparison to other studies. J Anim Sci 1998, 76:513-21.
- [3]Dourmad JY, Étienne M: Dietary lysine and threonine requirements of the pregnant sow estimated by nitrogen balance. J Anim Sci 2002, 80(8):2144-50.
- [4]Dourmad JY, Noblet J, Étienne M: Effect of protein and lysine supply on performance, nitrogen balance, and body composition changes of sows during lactation. J Anim Sci 1998, 76(2):542-50.
- [5]Rezaei R, Wang W, Wu Z, Dai Z, Wang J, Wu G: Biochemical and physiological bases for utilization of dietary amino acids by young Pigs. J Anim Sci Biotechnol 2013, 4(1):7. BioMed Central Full Text
- [6]Mitchell HH: Comparative nutrition of man and domestic animals. Academic Press, New York; 1964.
- [7]ARC: The nutrient requirements of pigs. Commonwealth Agricultural Bureaux, Slough, England; 1981.
- [8]Wang TC, Fuller MF: The optimum dietary amino acid pattern for growing pigs. 1. Experiments by amino acid deletion. Br J Nutr 1989, 62(1):77-89.
- [9]Fuller MF, McWilliam R, Wang TC, Giles LR: The optimum dietary amino acid pattern for growing pigs. 2. Requirements for maintenance and for tissue protein accretion. Br J Nutr 1989, 62:255-67.
- [10]Izquierdo OA, Wedekind KJ, Baker DH: Histidine requirement of the young pig. J Anim Sci 1988, 66(11):2886-92.
- [11]Chung TK, Baker DH: Ideal amino acid pattern for 10-kilogram pigs. J Anim Sci 1992, 70(10):3102-11.
- [12]Chung TK, Baker DH: Methionine requirement of pigs between 5 and 20 kilograms body weight. J Anim Sci 1992, 70(6):1857-63.
- [13]Hahn JD, Baker DH: Optimum ratio to lysine of threonine, tryptophan, and sulfur amino acids for finishing swine. J Anim Sci 1995, 73(2):482-9.
- [14]Stein HH, Seve B, Fuller MF, Moughan PJ, De Lange CFM: Invited review: amino acid bioavailability and digestibility in pig feed ingredients: terminology and application. J Anim Sci 2007, 85(1):172-80.
- [15]Van Milgen J, Valancogne A, Dubois S, Dourmad JY, Sève B, Noblet J: InraPorc: a model and decision support tool for the nutrition of growing pigs. Anim Feed Sci Technol 2008, 143:387-405.
- [16]NRC: Nutrient requirements of swine Eleventh revised edition ed. National Academy Press, Washington, DC, USA; 2012.
- [17]Boisen S: Ideal dietary amino acid profiles for pigs. In Amino acids in animal nutrition. Edited by D'Mello JPF. CABI Publishing, Oxon; 2003:157-68.
- [18]Coma J, Carrion D, Zimmerman DR: Use of plasma urea nitrogen as a rapid response criterion to determine the lysine requirement of pigs. J Anim Sci 1995, 73(2):472-81.
- [19]Elango R, Ball RO, Pencharz PB: Indicator amino acid oxidation: concept and application. J Nutr 2008, 138(2):243-6.
- [20]Van Milgen J, Gloaguen M, Le Floc'h N, Brossard L, Primot Y, Corrent E: Meta-analysis of the response of growing pigs to the isoleucine concentration in the diet. Animal 2012, 6(10):1601-8.
- [21]Robbins KR, Saxton AM, Southern LL: Estimation of nutrient requirements using broken-line regression analysis. J Anim Sci 2006, 84(13):E155-65.
- [22]Susenbeth A: Factors affecting lysine utilization in growing pigs: an analysis of literature data. Livest Prod Sci 1995, 43:193-204.
- [23]Susenbeth A. Optimum tryptophan:lysine ratio in diets for growing pigs: Analysis of literature data. Livest Sci. 2006;101(1–3):32–45. doi:10.1016/j.livprodsci.2005.09.008.
- [24]Simongiovanni A, Corrent E, Le Floc'h N, van Milgen J. Estimation of the tryptophan requirement in piglets by meta-analysis. Animal. 2012;6(04):594–602. doi:10.1017/S1751731111001960.
- [25]Dourmad JY, Étienne M, Valancogne A, Dubois S, Van Milgen J, Noblet J: InraPorc: a model and decision support tool for the nutrition of sows. Anim Feed Sci Technol 2008, 143:372-86.
- [26]Moughan PJ: Protein metabolism in the growing pig. In A quantitative biology of the pig. Edited by Kyriazakis I. CABI Publishing, Oxon, UK; 1998:299-331.
- [27]Barea R, Brossard L, Le Floc'h N, Primot Y, Van Milgen J: The standardized ileal digestible isoleucine-to-lysine requirement ratio may be lower than fifty percent in eleven- to twenty-three-kilogram piglets. J Anim Sci 2009, 87:4022-31.
- [28]Gloaguen M, Le Floc'h N, Primot Y, Corrent E, Van Milgen J: Response of piglets to the standardized ileal digestible isoleucine, histidine and leucine supply in cereal–soybean meal-based diets. Animal 2013, 7:901-8.
- [29]Sauvant D, Perez J-M, Tran G: Tables of composition and nutritional value of feed materials. Pigs, poultry, cattle, sheep, goats, rabbits, horses, fish. Paris, France, INRA Editions; 2004.
- [30]NRC: Nutrient requirements of swine. 10th revised edition ed. National Academy Press, Washington, DC, USA; 1998.
- [31]Brossard L, Dourmad JY, Rivest J, Van Milgen J: Modelling the variation in performance of a population of growing pigs as affected by lysine supply and feeding strategy. Animal 2009, 3(8):1114-23.
- [32]Dourmad JY, Noblet J, Père MC, Étienne M: Mating, pregnancy and prenatal growth. In A quantitative biology of the pig. Edited by Kyriazakis I. CABI Publishing, Oxon; 1999:129-53.
- [33]Gloaguen M, Le Floc'h N, Primot Y, Corrent E, Van Milgen J: Performance of piglets in response to the standardized ileal digestible phenylalanine and tyrosine supply in low-protein diets. Animal 2014, 8(9):1412-9.
- [34]Barea R, Brossard L, Le Floc'h N, Primot Y, Melchior D, Van Milgen J: The standardized ileal digestible valine-to-lysine requirement ratio is at least seventy percent in postweaned piglets. J Anim Sci 2009, 87(3):935-47.
- [35]Boisen S, Hvelplund T, Weisbjerg MR. Ideal amino acid profiles as a basis for feed protein evaluation. Livest Prod Sci. 2000;64(2–3):239–51. http://dx.doi.org/10.1016/S0301-6226(99)00146-3.
- [36]British Society of Animal Science: Nutrient requirement standards for pigs. British Society of Animal Science, Penicuik; 2003.
- [37]Gloaguen M, Le Floc'h N, Brossard L, Barea R, Primot Y, Corrent E, et al.: Response of piglets to the valine content in diet in combination with the supply of other branched-chain amino acids. Animal 2011, 5:1734-42.