Surgery combined with radiotherapy for the treatment of solitary plasmacytoma of the rib: a case report and review of the literature

Journal of Cardiothoracic Surgery

Zhefeng Zhang¹  Jian Li¹  Kun Gao¹  Huagang Liang¹  Lei Xue¹  Rui Jia¹ 

[1] Department of Thoracic Surgery, The First Hospital of Qinhuangdao, 258 Wenhua Road, Qinhuangdao 066000, Hebei, China

关键词: Radiotherapy;    Surgery;    Rib;    Plasmacytoma;   

Others  :  1230557
DOI  :  10.1186/s13019-015-0335-5

 received in 2015-03-17, accepted in 2015-10-05,  发布年份 2015

【 摘 要 】

Solitary plasmacytoma of the bone, especially of a single rib, is a rare disease. We present the case of a 44-year-old Han Chinese man who was diagnosed with a solitary plasmacytoma of the bone located in the right sixth rib. The patient presented with a 4-year history of continuous pain in the right chest area and moderate fever lasting 7 days. A chest roentgenogram showed a solitary expanding lesion in the right thorax, and chest computed tomography revealed an osteolytic tumor in the chest wall. The patient underwent complete en-bloc resection of the chest wall, including the ribs, muscle, and parietal pleura. Histologically, the resected mass was composed of abundant neoplastic plasma cells, and the diagnosis was confirmed to be a plasmacytoma of rib. The examination of marrow cells showed 9 % normal plasma cells among karyocytes without clonal disease. On postoperative day 14, the patient underwent thoracic radiotherapy with a total dose of 50 Gy. The patient remained asymptomatic during the 6-month follow-up period. Herein, we also review previous reports on solitary plasmacytomas of the rib. In summary, this report provides further insights for the diagnosis and effective treatment of this rare disease.

【 授权许可】

   
2015 Jia et al.

【 图 表 】

Fig. 1.

Fig. 2.

Fig. 3.

Fig. 4.

【 参考文献 】

• [1]Bataille R, Sany J. Solitary myeloma: clinical and prognostic features of a review of 114 cases. Cancer. 1981; 48:845-51.
• [2]Frassica DA, Frassica FJ, Schray MF, Sim FH, Kyle RA. Solitary plasmacytoma of bone: Mayo Clinic experience. In J Radiat Oncol Biol Phys. 1989; 16:43-8.
• [3]Woodruff RK, Malpas JS, White FE. Solitary plasmacytoma II: Solitary plasmacytoma of bone. Cancer. 1979; 43:2344-7.
• [4]Jackson A, Scarffe JH. Prognostic significance of osteopenia and immunoparesis at presentation in patients with solitary myeloma of bone. Eur J Cancer. 1990; 26:363-71.
• [5]Dimopoulos MA1, Moulopoulos LA, Maniatis A, Alexanian R. Solitary plasmacytoma of bone and asymptomatic multiple myeloma. Blood. 2000; 96:2037-44.
• [6]Wiltshaw E. The natural history of extramedullary plasmacytoma and its relation to solitary plasmacytoma of bone and myelomatosis. Medicine (Baltimore). 1976; 55:217-38.
• [7]Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E, Samson D. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol. 2004; 124:717-26.
• [8]Caffery T, Foy M. Plasmacytoma presenting as missing rib on chest film: a case report and review of the literature. J La State Med Soc. 2014; 166:63-6.
• [9]Tajima K, Uchida N, Azuma Y, Okada T, Sasamoto H, Yokoo H, Kuwano H. Surgical resection of a solitary plasmacytoma originating in a Rib. Ann Thorac Cardiovasc Surg. 2014; 20:609-12.
• [10]Santos VM, Brito EF, Paz BC, Leal CT. Rib plasmacytoma and IgA multiple myeloma with hyperviscosity syndrome. Arch Iran Med. 2012; 15:517-9.
• [11]Lee HY, Kim JI, Kim KN. Solitary plasmacytoma of the rib. Korean J Thorac Cardiovasc Surg. 2012; 45:269-71.
• [12]Singal R, Dalal U, Dalal AK, Attri AK, Gupta S, Raina R. Solitary plasmacytoma of the rib: A rare case. Lung India. 2011; 28:309-11.
• [13]Kodate M, Takagishi T, Osaki T. Plasmacytoma of chest wall. Kyobu Geka. 2010; 63:879-82.
• [14]Pattanayak L, Samantaray S, Rout N. Solitary plasmacytoma of the rib: a rare cytological detection. Indian J Cancer. 2010; 47:485-6.
• [15]Ketata W, Triki F, Msaad S, Ayadi L, Fouzi S, Ayadi H, Ayoub A. A rare localization of solitary plasmacytoma. Rev Pneumol Clin. 2009; 65:165-8.
• [16]Palao S, Masjuan J, López J, Calleja P. Solitary costal plasmacytoma: a rare cause of subacute demyelinating polyradiculoneuropathy. Neurologia. 2006; 21:265-8.
• [17]Bousnina S, Zendah I, Marniche K, Yalaoui S, El Mezni F, Megdiche ML, Chabbou A. Solitary plasmacytoma of the rib: A rare tumor not to miss. Rev Pneumol Clin. 2006; 62:243-6.
• [18]Wilkinson S, Forrester-Wood CP. Surgical resection of a solitary plasmacytoma originating in a rib of a patient with Castleman’s disease. Ann Thorac Surg. 2003; 75:1018-9.
• [19]George SM, Ratnakar KS, Shome DK, Nair R, AI Ajmi A. Plasmacytoma of the rib in young male. Asian Cardiovasc Thorac Ann. 2002; 10:282-4.
• [20]Sato Y, Hara M, Ogino H, Kaji M, Yamakawa Y, Wakita A, Tateyama H. CT-pathologic correlation in a case of solitary plasmacytoma of the rib. Radiat Med. 2001; 19:303-5.
• [21]Kadokura M, Tanio N, Nonaka M, Yamamoto S, Kataoka D, Kushima M, Kimura S, Nakamaki T, Sato I, Takaba T. A surgical case of solitary plasmacytoma of rib origin with biclonal gammopathy. Jpn J Clin Oncol. 2000; 30:191-5.
• [22]Mankodi AK, Rao CV, Katrak SM. Solitary plasmacytoma presenting as peripheral neuropathy: a case report. Neurol India. 1999; 47:234-7.
• [23]Hirai T, Hamada Y, Kanou T, Kobayashi J, Endo K, Morishita Y. Solitary plasmacytoma of the rib-a case report and review of Japanese literatures. Nihon Kyobu Geka Gakkai Zasshi. 1995; 43:205-9.
• [24]Carvajal Balaguera JJ, Mallagray Casas S, Dancausa Monge A, Canto Romero JJ. Horner’s syndrome associated with a solitary bone plasmacytoma of the first rib. Arch Bronconeumol. 1994; 30:410-3.
• [25]Ikeda T, Minakata Y, Inui H, Yukawa S, Nomoto H, Tsujimoto M. A case of plasmacytoma of the ribs with intrathoracic tumors. Nihon Kyobu Shikkan Gakkai Zasshi. 1992; 30:133-7.
• [26]Avilés A, Huerta-Guzmán J, Delgado S, Fernández A, Díaz-Maqueo JC. Improved outcome in solitary bone plasmacytomata with combined therapy. Hematol Oncol. 1996; 14:111-7.
• [27]Mendenhall CM, Thar TL, Million RR. Solitary plasmacytoma of bone and soft tissue. Int J Radiat Oncol Biol Phys. 1980; 6:1497-501.
• [28]Warsame R, Gertz MA, Lacy MQ, Kyle RA, Buadi F, Dingli D, Greipp PR, Hayman SR, Kumar SK, Lust JA, Russell SJ, Witzig TE, Mikhael J, Leung N, Zeldenrust SR, Rajkumar SV, Dispenzieri A. Trends and outcomes of modern staging of solitary plasmacytoma of bone. Am J Hematol. 2012; 87:647-51.