Impact of Male Circumcision among heterosexual HIV cases: comparisons between three low HIV prevalence countries

Israel Journal of Health Policy Research

Caroline Semaille¹  Françoise Cazein¹  Zohar Mor²  Ard van Sighem³  Eline Op de Coul⁴  Daniel Chemtob² 

[1] HIV/AIDS-STI-Hepatitis B and C Unit, Department of Infectious Diseases, Institut de Veille Sanitaire, Saint Maurice, France;Department of Tuberculosis and AIDS, Ministry of Health, Jerusalem 944727, Israel;Stichting HIV monitoring, Amsterdam, The Netherlands;Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands

关键词: The Netherlands;    Male circumcision;    Low HIV prevalence countries;    Israel;    HIV;    Heterosexual transmission;    France;   

Others  :  1223855
DOI  :  10.1186/s13584-015-0033-8

 received in 2015-02-25, accepted in 2015-07-11,  发布年份 2015

【 摘 要 】

Background

Studies performed in high-HIV prevalence countries showed a strong epidemiological association between male circumcision (MC) and the prevention of HIV transmission. We estimated the potential impact of MC on the general heterosexual population in low-HIV prevalence countries.

Methods

Cross-national comparisons, including data on newly diagnosed HIV cases among heterosexuals living in Israel (where almost all males undergo MC), to similar data from the Netherlands and France (where <10 % of males are circumcised) were performed. National data from HIV registers and Bureaus of Statistics for the period of 2004–2010, global rates, rates by sex, age, and year of HIV-diagnosis were compared. MC and potential biases were examined.

Results

Annual rates of new HIV diagnoses per 100,000 were significantly lower in Israel compared to the Netherlands and France (for men: 0.26–0.70, 1.91–2.28, and 2.69–3.47, respectively; for women: 0.10–0.34, 1.10–2.10 and 2.41–3.08, respectively). Similarly, HIV-rates were much lower in Israel when comparing by age groups. Although Gross National Income per capita in 2010 was lower in Israel compared to the Netherlands and France, access to HIV testing and treatment were not different between countries. Also, the number of sexual-partners and condom-use in the general population showed a high similarity between the countries.

Conclusions

The lower rate of HIV among heterosexuals in Israel compared to the Netherlands and France might be explained by MC routinely practiced in Israel, since other parameters of influence on HIV transmission were rather similar between the countries. However, recommendation for systematic MC in low HIV prevalence countries requires further investigations.

【 授权许可】

   
2015 Chemtob et al.

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