期刊论文详细信息
International Journal of Behavioral Nutrition and Physical Activity
Cost-effectiveness and cost-utility of a Web-based or print-delivered tailored intervention to promote physical activity among adults aged over fifty: an economic evaluation of the Active Plus intervention
Lilian Lechner3  Hein de Vries1  Aart N Mudde3  Catherine Bolman3  Silvia MAA Evers2  Denise A Peels3  Rianne HJ Golsteijn3 
[1]Department of Health Promotion, Maastricht University, Maastricht, The Netherlands
[2]Trimbos Institute, Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands
[3]Department of Psychology and Educational Sciences, Open University of the Netherlands, Heerlen, Heerlen, 6401 DL, The Netherlands
关键词: Quality of life;    Cost-utility;    Cost-effectiveness;    Physical activity;    Older adults;    Tailored intervention;   
Others  :  1136187
DOI  :  10.1186/s12966-014-0122-z
 received in 2014-03-25, accepted in 2014-09-19,  发布年份 2014
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【 摘 要 】

Background

The adverse health effects of insufficient physical activity (PA) result in high costs to society. The economic burden of insufficient PA, which increases in our aging population, stresses the urgency for cost-effective interventions to promote PA among older adults. The current study provides insight in the cost-effectiveness and cost-utility of different versions of a tailored PA intervention (Active Plus) among adults aged over fifty.

Methods

The intervention conditions (i.e. print-delivered basic (PB; N = 439), print-delivered environmental (PE; N = 435), Web-based basic (WB; N = 423), Web-based environmental (WE; N = 432)) and a waiting-list control group were studied in a clustered randomized controlled trial. Intervention costs were registered during the trial. Health care costs, participant costs and productivity losses were identified and compared with the intervention effects on PA (in MET-hours per week) and quality-adjusted life years (QALYs) 12 months after the start of the intervention. Cost-effectiveness ratios (ICERs) and cost-utility ratios (ICURs) were calculated per intervention condition. Non-parametric bootstrapping techniques and sensitivity analyses were performed to account for uncertainty.

Results

As a whole (i.e. the four intervention conditions together) the Active Plus intervention was found to be cost-effective. The PB-intervention (ICER = €-55/MET-hour), PE-intervention (ICER = €-94/MET-hour) and the WE-intervention (ICER = €-139/MET-hour) all resulted in higher effects on PA and lower societal costs than the control group. With regard to QALYs, the PB-intervention (ICUR = €38,120/QALY), the PE-intervention (ICUR = €405,892/QALY) and the WE-intervention (ICUR = €-47,293/QALY) were found to be cost-effective when considering a willingness-to-pay threshold of €20,000/QALY. In most cases PE had the highest probability to be cost-effective.

Conclusions

The Active Plus intervention was found to be a cost-effective manner to increase PA in a population aged over fifty when compared to no-intervention. The tailored Active Plus intervention delivered through printed material and with additional environmental information (PE) turned out to be the most cost-effective intervention condition as confirmed by the different sensitivity analyses. By increasing PA at relatively low costs, the Active Plus intervention can contribute to a better public health.

Trial registration

Dutch Trial Register: NTR2297 webcite

【 授权许可】

   
2014 Golsteijn et al.; licensee BioMed Central Ltd.

【 预 览 】
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【 参考文献 】
  • [1]World Health Organisation: Global recommendations on physical activity for health. In Global recommendations on physical activity for health. Geneva: World Health Organisation; 2010.
  • [2]Hobbs N, Godfrey A, Lara J, Errington L, Meyer TD, Rochester L, White M, Methers JC, Sniehotta FF: Are behavioural interventions effective in increasing physical activity at 12 to 36 months in adults aged 55 to 70 years? A systematic review and meta-analysis. BMC Medicine 2013, 11:75. BioMed Central Full Text
  • [3]Lee IM, Shiroma EJ, Lobelo F, Puska P, Blair SN, Katzmarzyk PT: Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. Lancet 2012, 380:219-229.
  • [4]Europe WHO: Steps to health: a european framework to promote physical activity for health. WHO, Europe; 2007.
  • [5]Hagberg L: Cost-effectiveness of the promotion of physical activity in health care. Umea University, Department of Public Health and Clinical Medicine, Umea; 2007.
  • [6]Oldridge NB: Economic burden of physical inactivity: healthcare costs associated with cardiovascular disease. Eur J Cardiovasc Prev Rehabil 2008, 15:130-139.
  • [7]Colman R, Walker S: The cost of physical inactivity in British Columbia. In Genuine Progress Index for Atlantic Canada - Measuring sustainable development. Ministry of Health Planning, Glen Haven; 2004.
  • [8]Sevick MA, Dunn AL, Morrow MS, Marcus BH, Chen GJ, Blair SN: Cost-effectiveness of lifestyle and structured exercise interventions in sedentary adults. Results from project ACTIVE. Am J Prev Med 2000, 19:1-8.
  • [9]Garrett S, Elley CR, Rose SB, O’Dea D, Lawton BA, Dowell AC: Are physical activity interventions in primary care and the community cost-effective? A systematic review of the evidence. Br J Gen Pract 2011, 61:e125-133.
  • [10]At least five a week: Evidence on the impact of physical activity and its relationship to health. Department of Health, London; 2004.
  • [11]Hallal PC, Andersen LB, Bull FC, Guthold R, Haskell W, Ekelund U: Global physical activity levels: surveillance progress, pitfalls, and prospects. Lancet 2012, 380:247-257.
  • [12]Woodcock J, Franco OH, Orsini N, Roberts I: Non-vigorous physical activity and all-cause mortality: systematic review and meta-analysis of cohort studies. Int J Epidemiol 2011, 40:121-138.
  • [13]De Jong A, Van Duin C: Regionale prognose 2009–2040: Vergrijzing en omslag van groei naar krimp. Centraal Bureau voor de Statistiek, Heerlen; 2010.
  • [14]Martinson BC, Crain AL, Pronk NP, O’conner PJ, Maciosek MV: Changes in physical activity and short-term changes in health care charges: a prospective cohort study of older adults. Prev Med 2003, 37:319-326.
  • [15]Noar SM, Benac CN, Harris MS: Does tailoring matter? Meta-analytic review of tailored print health behavior change interventions. Psychol Bull 2007, 133:673-693.
  • [16]Krebs P, Prochaska JO, Rossi JS: A meta-analysis of computer-tailored interventions for health behaviour change. Prev Med 2010, 51:214-221.
  • [17]Peels DA, Bolman C, Golsteijn RHJ, De Vries H, Mudde AN, Van Stralen MM, Lechner L: Long-term efficacy of a tailored physical activity intervention among older adults. Int J Behav Nutr Phys Act 2013, 10:104. BioMed Central Full Text
  • [18]Van Keulen H, Bosman J, van Tulder M, Severens J, de Vries H, Brug J, Mesters I: Cost-effectiveness of tailored print communication, telephone motivational interviewing, and a combination of the two: results of an economic evaluation alongside the Vitalum randomized controlled trial. Int J Behav Nutr Phys Act 2010, 7:64. BioMed Central Full Text
  • [19]Van Stralen MM, De Vries H, Mudde AN, Bolman C, Lechner L: The Long-Term Efficacy of Two Computer-Tailored Physical Activity Interventions for Older Adults: Main Effects and Mediators. Health Psychol 2011, 30:442-452.
  • [20]Van Stralen MM, Kok G, De Vries H, Mudde AN, Bolman C, Lechner L: The Active Plus protocol: systematic development of two theory and evidence-based tailored physical activity interventions for the over-fifties. BMC Public Health 2008, 8:399. BioMed Central Full Text
  • [21]Peels DA, Van Stralen MM, Bolman C, Golsteijn RHJ, De Vries H, Mudde AN, Lechner L: The Development of a Web-Based Computer Tailored Advice to Promote Physical Activity Among People Older Than 50 Years. J Med Internet Res 2012, 14:e39.
  • [22]Joseph RP, Durant NH, Benitez TJ, Pekmezi DW: Internet-based Physical Activity Interventions. Am J Lifestyle Med 2014, 8:42.
  • [23]Tate DF, Finkelstein EA, Khavjou O: Cost effectiveness of internet interventions: review and recommendations. Ann Behav Med 2009, 38:40-45.
  • [24]Lewis B, Williams D, Neighbors C, Jakicic J, Marcus B: Cost analysis of internet vs. print interventions for physical activity promotion. Psychol Sport Exerc 2010, 11:246-249.
  • [25]Sevick MA, Napolitano MA, Papandonatos GD, Gordon AJ, Reiser LM, Marcus BH: Cost-effectiveness of alternative approaches for motivating activity in sedentary adults: results of Project STRIDE. Prev Med 2007, 45:54-61.
  • [26]De Salazar L, Jackson S, Shiell A, Rice M: Guide to Economic Evaluation in Health Promotion. Pan American Health Organization, Washington D.C; 2007.
  • [27]Hakkaart-van Roijen L, Tan S, Bouwmans C: Handleiding voor kostenonderzoek: Methoden en standaard kostprijzen voor economische evaluaties in de gezondheidszorg (in Dutch). College voor Zorgverzekeringen, Rotterdam; 2010.
  • [28]Peels DA, Bolman C, Golsteijn RHJ, De Vries H, Mudde AN, Van Stralen MM, Lechner L: Differences in Reach and Attrition between Web-based or Print-delivered Tailored Interventions among Adults aged over Fifty. J Med Internet Res 2012, 14:e179.
  • [29]Van Stralen MM, De Vries H, Mudde AN, Bolman C, Lechner L: The working mechanisms for an environmentally tailored physical activity intervention for older adults: a randomized controlled trial. Int J Behav Nutr Phys Act 2009, 6:83. BioMed Central Full Text
  • [30]Peels DA, De Vries H, Bolman C, Golsteijn RHJ, Van Stralen MM, Mudde AN, Lechner L: Differences in the use and appreciation of a Web-based or printed computer tailored physical activity intervention for people aged over fifty. Health Educ Res 2013, 28:715-731.
  • [31]Berndt NC: Smoking cessation in patients with coronary heart disease: Determinants of quitting and comparison of the (cost)effectiveness and feasibility of a telephone and face-to-face counseling intervention. Open University, Department of Psychology, Heerlen; 2013.
  • [32]Drummond MF, O’Brien BJ, Sculpher MJ, Thorrance GW, Stoddart GL: Methods for the economic evaluation of health care programmes. Oxford University Press, Oxford; 2005.
  • [33]Glick HA, Doshi JA, Sonnad SS, Polsky D: Economic Evaluations in Clinical Trials. Oxford University Press, Oxford; 2007.
  • [34]De Wit GA, Tariq L, Van Gils PF, Panneman M: Over euro en effect: handleiding voor economisch evaluatieonderzoek bij gezondheidsbevordering (in Dutch). Consument en Veiligheid, Amsterdam; 2010.
  • [35]Thorn JC, Coast J, Cohen D, Hollingworth W, Knapp M, Noble SM, Ridyard C, Wordsworth S, Hughes D: Resource-use measurement based on patient recall: Issues and challenges for economic evaluation. Appl Health Econ Health Policy 2013, 11:155-161.
  • [36]Wendel-Vos GCW, Schuit AJ, Saris WH, Kromhout D: Reproducibility and relative validity of the short questionnaire to assess health-enhancing physical activity. J Clin Epidemiol 2003, 56:1163-1169.
  • [37]Wagenmakers R, Van den Akker-Scheek I, Groothoff JW, Zijlstra W, Bulstra SK, Kootstra JWJ, Wendel-Vos W, van Raaij JJAM, Stevens M: Reliability and validity of the short questionnaire to assess health-enhancing physical actiivty (SQUASH) in patients after total hip arthroplasty. BMC Muskuloskeletal Disord 2008, 9:141. BioMed Central Full Text
  • [38]EuroQol-- a new facility for the measurement of health-related quality of life Health Policy 1990, 16:199-208.
  • [39]Sculpher MJ: NICE’s 2008 Methods Guide: sensible concolidation or opportunities missed? Pharmacoeconomics 2008, 26:721-724.
  • [40]Lamers LM, McDonnell J, Stalmeier PF, Krabbe PF, Busschbach JJ: The Dutch tariff: results and arguments for an effective design for national EQ-5D valuation studies. Health Econ 2006, 15:1121-1132.
  • [41]Smit ES, Evers SMAA, De Vries H, Hoving C: Cost-effectiveness and cost-utility of internet-based computer tailoring for smoking cessation. J Med Internet Res 2013, 15:e57.
  • [42]Van Wier MF, Dekkers JC, Bosmans JE, Heymans MW, Hendriksen IJM, Pronk NP, Van Mechelen W, Van Tulder MW: Economic evaluation of a weight control program with e-mail and telephone counseling among overweight employees: a randomized controlled trial. Int J Behav Nutr Phys Act 2012, 9:112. BioMed Central Full Text
  • [43][www.medicijnkosten.nl] webcite CVZ: Diemen: College voor Zorgverzekeringen; 2013. .
  • [44][http://statline.cbs.nl/statweb] webcite Statline. []
  • [45]van Asselt AD, van Mastrigt GA, Dirksen CD, Arntz A, Severens JL, Kessels AG: How to deal with cost differences at baseline. Pharmacoeconomics 2009, 27:519-528.
  • [46]Zinnige en duurzame zorg: transparante keuzen in de zorg voor een houdbaar zorgstelsel. Raad voor de Volksgezondheid en Zorg, Zoetermeer; 2006.
  • [47]Boersma C, Broere A, Postma M: Quantification of the potential impact of cost-effectiveness thresholds on dutch drug expenditures using retrospective analysis. Value Health 2010, 13:853-856.
  • [48]Dolan P: Modeling vaulations for EuroQol health states. Med Care 1997, 35:1095-1108.
  • [49]Muller-Riemenschneider F, Reinhold T, Willich S: Cost-effectiveness of interventions promoting physical activity. Br J Sports Med 2009, 43:70-76.
  • [50]Elley R, Kerse N, Arroll B, Swinburn B, Ashton T, Robinson E: Cost-effectiveness of physical activity counseling in general practice. N Z Med J 2004, 117:U1216.
  • [51]Eriksson MK, Hagberg L, Lindholm L, Malmgren-Olssen EB, Osterlind J, Eliasson M: Quality of life and cost-effectiveness of a 3 year trial of lifestyle intervention in primary health care. Arch Intern Med 2010, 170:1470-1479.
  • [52]Bize R, Johnson JA, Plotnikoff RC: Physical activity level and health-related quality of life in general adult population: a systematic review. Prev Med 2007, 45:401-415.
  • [53]Wendel-Vos GCW, Schuit AJ, Tijhuis MAR, Kromhout D: Leisure time physical activity and health-related quality of life: cross-sectional and longitudinal associations. Qual Life Res 2004, 13:667-677.
  • [54]Kuntz K, Weinstein M: Modelling in economic evaluation. In Economic evaluation in health care: merging theory with practice. Edited by Drummond MF, McGuire A. Oxford university press, New York; 2010.
  • [55]Lucas RE: Adaptation and the set-point model of subjective well-being - Does happiness change after major life events? Curr Dir Psychol Sci 2007, 16:75-79.
  • [56]Diener E, Lucas RE, Scollon CN: Beyond the hedonic treadmill: revising the adaptation theory of well-being. Am Psychol 2006, 61:305-314.
  • [57]Sprangers M, Schwartz C: Integrating response shift into health-related quality of life research: a theoretical model. Soc Sci Med 1999, 48:1507-1515.
  • [58]Kopec JA, Willison KD: A comparative review of four preference-weighted measures of health-related quality of life. J Clin Epidemiol 2003, 56:317-325.
  • [59]Lorgelly PK, Lawson KD, Fenwick EA, Briggs AH: Outcome measurement in economic evaluation of public health interventions: a role for the capability approach? Int J Environ Res Public Health 2010, 7:2274-2289.
  • [60]Herdman M, Gudex C, Lloyd A, Janssen MF, Kind P, Parkin D, Bonsel G, Badia X: Development and preliminary testing of the new five-level version of EQ-5D (EQ-5D-5 L). Qual Life Res 2011, 20:1727-1736.
  • [61]Lee KJ, Simpson JA: Introduction to multiple imputation for dealing with missing data. Respirology 2014, 19:162-167.
  • [62]Flay BR: Efficacy and effectiveness trials (and other phases of research) in the development of health promotion programs. Prev Med 1986, 15:451-474.
  • [63]Flay BR, Biglan A, Boruch RF, Castro FG, Gottfredson D, Kellam S, Moscicki EK, Schinke S, Valentine JC, Ji P: Standards of Evidence: Criteria for efficacy, effectiveness and dissemination. Prev Sci 2005, 6:151-175.
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