Excess cost of non-remission among outpatients with major depressive disorder

International Journal of Mental Health Systems

Jin Pyo Hong³  Chang Hwa Lee⁴  Jai Sung Noh²  Chang Uk Lee⁵  Kwang-Hun Lee⁶  Hyo-Jin Kim¹  Hong Jin Jeon⁷  Jong-Min Woo⁸ 

[1] OR/EBM Team, Market Access Division, Pfizer Pharmaceuticals Korea Limited, Seoul, Korea;Department of Psychiatry, Ajou University School of Medicine, Suwon, Korea;Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea;Department of Psychiatry, Eulji University School of Medicine, Daejeon, Korea;Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea;Department of Psychiatry, Dongguk University College of Medicine, Gyeongju, Korea;Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, USA;Stress Research Institute, Inje University, Seoul, Korea

关键词: Remission;    Presenteeism;    Lost productive time;    HPQ;    Major depressive disorder;   

Others  :  1135959
DOI  :  10.1186/1752-4458-8-42

 received in 2014-05-13, accepted in 2014-10-16,  发布年份 2014

【 摘 要 】

Background

The purpose of this study was to assess the economic benefit of achieving remission among outpatients with major depressive disorder (MDD) who are currently employed in Korea.

Methods

Cross-sectional observational study. A total of 337 outpatients with MDD with paid jobs were recruited from 14 psychiatric clinics in Korea and were then divided into three groups as follows: new visit group (n = 128), remitted group (n = 100) and non-remitted group (n = 109). The 17-item Hamilton Depression Rating Scale (HAM-D) was used to decide whether a patient should be assigned to the remitted or non-remitted group. Direct medical and non-medical costs were measured via interview with the subjects. The World Health Organization Health and Work Performance Questionnaire (HPQ) were applied in order to measure the lost productive time (LPT) and related productivity costs.

Results

The three groups did not show a significant difference in direct medical cost. However, the difference between the remitted group and non-remitted group was statistically significant (25.49 ± 52.99 vs. 44.79 ± 126.55, χ² = 12.99, p = 0.0015). The remitted group demonstrated a significant improvement in productivity (particularly presenteeism) when compared with the new visit group (Z = −3.29, p = 0.001). Although the non-remitted group received treatment at psychiatric clinics similar to the remitted group, it lost 33 more working hours per month, which is compatible to $332 per month.

Conclusion

These results suggest the economic importance of achieving remission in treating depression.

【 授权许可】

   
2014 Woo et al.; licensee BioMed Central Ltd.

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