Sudden death in a young female with an under-recognised coronary anomaly

Diagnostic Pathology

Vincenzo Arena²  Giuseppe Vetrugno¹  Vincenzo M Grassi¹  Fabio De-Giorgio¹ 

[1] Institute of Legal Medicine, Catholic University, Medical School, Rome, Italy;Institute Pathologic Anatomy, Catholic University, Medical School, Rome, Italy

关键词: Left descending artery;    Heart;    Septal coronary branches;    Agenesia;    Sudden death;   

Others  :  807406
DOI  :  10.1186/1746-1596-8-41

 received in 2012-11-12, accepted in 2013-01-23,  发布年份 2013

【 摘 要 】

Anomalies of coronary number and course represent an opinion-dividing topic in cardiopathology, particularly for their relationship with sudden cardiac death.

To the best of our knowledge, we herein report the first fatal case of a young female whose coronary anatomy was characterised by the absence of any septal perforator branch in the proximal segment of the LAD.

This case could be useful for pathologists, coronary angiographers, and interventional cardiologists in detecting this infrequent anomaly, thus providing a more accurate estimation of its incidence.

Virtual Slides

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【 授权许可】

   
2013 De-Giorgio et al; licensee BioMed Central Ltd.

【 图 表 】

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【 参考文献 】

• [1]Angelini P, Velasco JA, Flamm S: Coronary anomalies: incidence, pathophysiology, and clinical relevance. Circulation 2002, 105:2449-2454.
• [2]Silver MD, Gotlieb AI, Schoen FJ: Cardiovascular pathology. New York, NY: Churchill Livingstone; 2001.
• [3]Trivellato M, Angelini P, Leachman RD: Variations in coronary artery anatomy: Normal versus abnormal. Cardiovasc Dis 1980, 7:357-370.
• [4]James TN, Burch GE: Blood supply of the human interventricular septum. Circulation 1958, 17:391-396.
• [5]Verna E, Santarone M, Boscarini M, Ghezzi I, Repetto S: Unusual origin and course of the first septal branch of the left coronary artery: angiographic recognition. Cardiovasc Intervent Radiol 1988, 11:146-149.
• [6]Finkbeiner WE, Ursell PC, Davis RL: Autopsy Pathology: A Manual and Atlas: Expert Consult - Online and Print. Philadelphia, PA: Elsevier Health Sciences; 2009.
• [7]De Giorgio F, Abbate A, Vetrugno G, Capelli A, Arena V: Non-atherosclerotic coronary pathology causing sudden death. J Clin Pathol 2007, 60:94-97.
• [8]Bello S, Neri M, Riezzo I, Othman MS, Turillazzi E, Fineschi V: Cardiac beriberi: morphological findings in two fatal cases. Diagn Pathol 2011, 6:8. BioMed Central Full Text
• [9]De-Giorgio F, Arena V: Ostial plication: A rarely reported cause of sudden death. Diagn Pathol 2010, 5:15. BioMed Central Full Text
• [10]Basso C, Burke M, Fornes P, Gallagher PJ, de Gouveia RH, Sheppard M, Thiene G, van der Wal A: Guidelines for autopsy investigation of sudden cardiac death. Virchows Arch 2008, 452:11-18.
• [11]Thiene G, Basso C: Sudden coronary death–not always atherosclerotic. Heart 2010, 96:1084-1085.
• [12]Dabizzi RP, Caprioli G, Aiazzi L, Castelli C, Baldrighi G, Parenzan L, Baldrighi V: Distribution and anomalies of coronary arteries in tetralogy of fallot. Circulation 1980, 61:95-102.
• [13]Wei J, Tang J, Xia L, Chen X, Wang DW: A case of Arrhythmogenic right ventricular cardiomyopathy without arrhythmias. Diagn Pathol 2012, 7:67. BioMed Central Full Text