Eating a healthy lunch improves serum alanine aminotransferase activity

Lipids in Health and Disease

Masao Sato¹  Bungo Shirouchi¹  Airi Komine¹  Kayoko Yazumi³  Kaori Yagi²  Masako Iwamoto³ 

[1] Laboratory of Nutrition Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School of Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, 812-8581, Japan;Graduate School of Health and Nutrition Sciences, Nakamura Gakuen University, 5-7-1 Befu, Jonan-ku, Fukuoka, 814-0198, Japan;Department of Nutritional Sciences, Faculty of Nutritional Sciences, Nakamura Gakuen University, 5-7-1 Befu, Jonan-ku, Fukuoka, 814-0198, Japan

关键词: Cafeteria;    Lunch;    Non-alcoholic fatty liver;    Serum alanine aminotransferase (ALT);    Dietary intervention;    ‘Once-a-day’;   

Others  :  833802
DOI  :  10.1186/1476-511X-12-134

 received in 2013-08-02, accepted in 2013-09-13,  发布年份 2013

【 摘 要 】

Background

Nutritional guidance and diet control play important roles in the treatment of obesity and non-alcoholic fatty liver. However, in Japan, nutritional guidance is difficult to provide in practice. Therefore, we evaluated the effects of providing the ‘once-a-day’ intervention of a healthy lunch on various metabolic parameters.

Methods

For a 1-month preparatory period, 10 subjects generally consumed the lunches that were provided by the worksite cafeteria. This was followed by a 1-week washout period, after which, the subjects consumed healthy, low-calorie, well-balanced lunches for a 1-month test period. After the preparatory and test periods, blood samples were obtained from all subjects. The serum levels of indices relevant to metabolic syndrome and fatty liver were measured.

Results

Serum alanine aminotransferase activity significantly decreased by 20.3% after the healthy intervention. However, the indices of metabolic syndrome did not significantly change. Analysis of the relationship between serum alanine aminotransferase activity and nutrient content indicated that the improvement of serum alanine aminotransferase status was due to the higher vegetable content and lower animal-source protein of the meals provided.

Conclusions

In summary, the ‘once-a-day’ intervention of providing a healthy lunch improved serum alanine aminotransferase status. A diet high in vegetables and low in animal-based protein is important in maintaining a healthy condition.

【 授权许可】

   
2013 Iwamoto et al.; licensee BioMed Central Ltd.

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