The association between polyunsaturated fatty acids and depression among Iranian postgraduate students in Malaysia

Lipids in Health and Disease

Sanaz Aazami¹  Teymoor Yary¹ 

[1] Department of Nutrition, Faculty of Food Sciences and Engineering (FFSE), Science and Research Branch, Islamic Azad University (SRBIAU), Hesarak, Tehran, I.R.Iran

关键词: neurotransmitter;    inflammation;    depression;    Polyunsaturated fatty acids (PUFAs);   

Others  :  1212531
DOI  :  10.1186/1476-511X-10-151

 received in 2011-07-29, accepted in 2011-08-24,  发布年份 2011

【 摘 要 】

Background

The incidence of depression is expected to increase over the next 20 years, and many people will have to deal with it. It has been reported that up to 40% of university students experience levels of depression. Several negative consequences are associated with depression symptoms, such as memory impairment, suicide, and substance abuse. Recently, researchers have been studying possible associations between depression and polyunsaturated fatty acids (PUFAs), which may modify depression symptoms. The aim of the present study was to find an association between PUFA levels and depression among Iranian postgraduate students in Malaysia.

Methods

This cross-sectional study was conducted in 2011 with 402 Iranian postgraduate students who were studying in Malaysia. The participants included 173 (43%) women and 229 (57%) men, and the mean age of the participants was 32.54 ± 6.22 years.

Results

After adjustment for several potential confounders including sex, age, BMI, PUFAs, MUFAs, and SFAs, monthly expenses, close friends, living in campus, smoking, education, and marital status in a logistic regression model, an inverse relationship was found between depression symptoms and the dietary intake of PUFAs.

Conclusion

We found an inverse association between PUFA intake and depression symptoms in Iranian postgraduate students in Malaysia. We, therefore, concluded that long-term intake of PUFAs may modify or prevent depression symptoms.

【 授权许可】

   
2011 Yary and Aazami; licensee BioMed Central Ltd.

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