MicroRNA-7: a promising new target in cancer therapy

Cancer Cell International

Lin Xu²  Dan Tian²  Chao Chen²  Nalin Qin²  Ya Zhou¹  Yijing Tao²  Juanjuan Zhao² 

[1] Department of Medical Physics, Zunyi Medical College, Guizhou 563000, China;Department of Immunology, Zunyi Medical College, Guizhou 563000, People’s Republic of China

关键词: Treatment;    Diagnosis;    MiR-7;    Tumors;   

Others  :  1233578
DOI  :  10.1186/s12935-015-0259-0

 received in 2015-09-22, accepted in 2015-10-20,  发布年份 2015

【 摘 要 】

The incidence of tumors with life-threatening effects has increased gradually over time; however, the mechanisms involved in tumor development have not been fully elucidated. Recent studies have shown that microRNA-7 (miR-7), which is endogenous non-coding RNA molecules of approximately 23 nucleotides, plays an important role in the occurrence and development of tumors as a key tumor suppressor. Mechanistic evidence showed that miR-7 is closely related to the growth, metastasis, and prognosis of various malignant tumors through regulating different target molecules, which suggest that miR-7 may be a new target for the clinical diagnosis and treatment of various tumors. In this review, we summarize current knowledge of the relationship between miR-7 and tumor development, diagnosis, and treatment.

【 授权许可】

   
2015 Zhao et al.

【 图 表 】

Fig.1.

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