The phantoms of a high-seven - or - why do our thumbs stick out?

Frontiers in Zoology

Axel Meyer¹  Joost M. Woltering¹ 

[1] Chair in Zoology and Evolutionary Biology, Department of Biology, University of Konstanz, Universitätsstraße 10, Konstanz, 78457, Germany

关键词: Post-axial;    Pre-axial;    Digit;    Limb;    Fin;    Tetrapod;    Pentadactyly;    Thumb;   

Others  :  1226114
DOI  :  10.1186/s12983-015-0117-x

 received in 2015-07-13, accepted in 2015-09-05,  发布年份 2015

【 摘 要 】

The earliest tetrapods had hands and feet with up to eight digits but this number was subsequently reduced during evolution. It was assumed that lineages with more than five digits no longer exist but investigations of clawed-frogs now indicate that they posses a rudimentary or atavistic sixth digit in their hindlimb. A recent reevaluation of the stem tetrapod Ichthyostega predicts that its seven digits evolved from two different types of ancestral fin radials, pre-axial and post-axial. In this context we now ask the question, should we consider a pre-axial origin of the thumb as reason for its unique genetic signature?

【 授权许可】

   
2015 Woltering and Meyer.

【 图 表 】

Fig. 1.

【 参考文献 】

• [1]Niedzwiedzki G, Szrek P, Narkiewicz K, Narkiewicz M, Ahlberg PE. Tetrapod trackways from the early Middle Devonian period of Poland. Nature. 2010; 463(7277):43-8.
• [2]Coates MI, Clack JA. Polydactyly in the Earliest Known Tetrapod Limbs. Nature. 1990; 347(6288):66-9.
• [3]Coates MI, Ruta R. Skeletal changes in the transition from fins to limbs. In: Fins into limbs. Hall BK, editor. The University of Chicago Press, Chicago; 2007: p.15-37.
• [4]Clack JA. An early tetrapod from 'Romer's Gap'. Nature. 2002; 418(6893):72-6.
• [5]Laurin M, Girondot M, de Ricqles A. Early tetrapod evolution. Trends Ecol Evol. 2000; 15(3):118-23.
• [6]Anderson JS, Smithson T, Mansky CF, Meyer T, Clack J. A Diverse Tetrapod Fauna at the Base of 'Romer's Gap'. PloS one. 2015; 10(4): Article ID e0125446
• [7]Galis F, van Alphen JJM, Metz JAJ. Why five fingers? Evolutionary constraints on digit numbers. Trends Ecol Evol. 2001; 16(11):637-46.
• [8]Hayashi S, Kobayashi T, Yano T, Kamiyama N, Egawa S, Seki R et al.. Evidence for an amphibian sixth digit. Zoological letters. 2015; 1(17):1-9.
• [9]Fabrezi M. A survey of prepollex and prehallux variation in anuran limbs. Zool J Linn Soc-Lond. 2001; 131(2):227-48.
• [10]Welten MC, Verbeek FJ, Meijer AH, Richardson MK. Gene expression and digit homology in the chicken embryo wing. Evolution & development. 2005; 7(1):18-28.
• [11]Shubin NH, Alberch P. A morphogenetic approach to the origin and basic organization of the tetrapod limb. In: Evolutionary Biology. Hecht MK, Wallace B, Prance GT, editors. Plenum Press, New York; 1986: p.319-287.
• [12]Cohn MJ, Lovejoy CO, Wolpert L, Coates MI. Branching, segmentation and the metapterygial axis: pattern versus process in the vertebrate limb. BioEssays. 2002; 24(5):460-5.
• [13]Mednikov D. Urodelans, Ichthyostega and the Origin of the Tetrapod Limb. Paleontological Journal. 2014; 48(10):1092-103.
• [14]Johanson Z, Joss J, Boisvert CA, Ericsson R, Sutija M, Ahlberg PE. Fish fingers: Digit homologues in Sarcopterygian fish fins. J Exp Zool Part B. 2007; 308B(6):757-68.
• [15]Shubin N. The evolution of paired fins and the origin of tetrapod limbs. In: Evolutionary Biology. Knecht MK, editor. Plenum Press, New York; 1995: p.39-86.
• [16]Sordino P, van der Hoeven F, Duboule D. Hox gene expression in teleost fins and the origin of vertebrate digits. Nature. 1995; 375(6533):678-81.
• [17]Woltering JM, Noordermeer D, Leleu M, Duboule D. Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits. PLoS biology. 2014; 12(1):e1001773.
• [18]Gehrke AR, Schneider I, de la Calle-Mustienes E, Tena JJ, Gomez-Marin C, Chandran M et al.. Deep conservation of wrist and digit enhancers in fish. Proceedings of the National Academy of Sciences of the United States of America. 2015; 112(3):803-8.
• [19]Woltering JM, Duboule D. The origin of digits: expression patterns versus regulatory mechanisms. Developmental cell. 2010; 18(4):526-32.
• [20]Freitas R, Gomez-Marin C, Wilson JM, Casares F, Gomez-Skarmeta JL. Hoxd13 contribution to the evolution of vertebrate appendages. Developmental cell. 2012; 23(6):1219-29.
• [21]Scherz PJ, McGlinn E, Nissim S, Tabin CJ. Extended exposure to Sonic hedgehog is required for patterning the posterior digits of the vertebrate limb. Developmental biology. 2007; 308(2):343-54.
• [22]Chiang C, Litingtung Y, Harris MP, Simandl BK, Li Y, Beachy PA et al.. Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function. Developmental biology. 2001; 236(2):421-35.
• [23]Ros MA, Dahn RD, Fernandez-Teran M, Rashka K, Caruccio NC, Hasso SM et al.. The chick oligozeugodactyly (ozd) mutant lacks sonic hedgehog function in the limb. Development. 2003; 130(3):527-37.
• [24]Wang Z, Young RL, Xue HL, Wagner GP. Transcriptomic analysis of avian digits reveals conserved and derived digit identities in birds. Nature. 2011; 477(7366):583-U345.
• [25]Montavon T, Le Garrec JF, Kerszberg M, Duboule D. Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness. Genes & development. 2008; 22(3):346-59.
• [26]Wagner GP, Vargas AO. On the nature of thumbs. Genome biology. 2008; 9(3):213. BioMed Central Full Text
• [27]Montavon T, Soshnikova N, Mascrez B, Joye E, Thevenet L, Splinter E et al.. A regulatory archipelago controls Hox genes transcription in digits. Cell. 2011; 147(5):1132-45.
• [28]James MA, Green HD, McCarroll HR, Manske PR. The association of radial deficiency with thumb hypoplasia. The Journal of bone and joint surgery American volume. 2004; 86-A(10):2196-205.
• [29]Reno PL, McCollum MA, Cohn MJ, Meindl RS, Hamrick M, Lovejoy CO. Patterns of correlation and covariation of anthropoid distal forelimb segments correspond to Hoxd expression territories. Journal of experimental zoology Part B, Molecular and developmental evolution. 2008; 310(3):240-58.
• [30]Wagner GP, Gauthier JA. 1,2,3 = 2,3,4: a solution to the problem of the homology of the digits in the avian hand. Proceedings of the National Academy of Sciences of the United States of America. 1999; 96(9):5111-6.
• [31]Salinas-Saavedra M, Gonzalez-Cabrera C, Ossa-Fuentes L, Botelho JF, Ruiz-Flores M, Vargas AO. New developmental evidence supports a homeotic frameshift of digit identity in the evolution of the bird wing. Frontiers in zoology. 2014; 11(1):33. BioMed Central Full Text
• [32]Onimaru K, Kuraku S, Takagi W, Hyodo S, Sharpe J, Tanaka M. A shift in anterior-posterior positional information underlies the fin-to-limb evolution. eLife. 2015;4. doi:10.7554/eLife.07048.
• [33]Freitas R, Zhang G, Cohn MJ. Biphasic Hoxd gene expression in shark paired fins reveals an ancient origin of the distal limb domain. PloS one. 2007; 2(8):e754.
• [34]Joss JM. The Australian lungfish, Neoceratodus forsteri: a personal story. General and comparative endocrinology. 2011; 173(1):1-3.