Journal of Medical Case Reports | |
Cerebral venous sinus thrombosis presenting with diplopia in pregnancy: a case report | |
Embong Zunaina2  Zakariah Sakinah1  Yusoff Munira2  | |
[1] Department of Ophthalmology, Hospital Raja Perempuan Zainab II, 15886 Kota Bharu, Kelantan, Malaysia;Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia | |
关键词: Pregnancy; Diplopia; Cerebral venous sinus thrombosis; | |
Others : 1195361 DOI : 10.1186/1752-1947-6-336 |
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received in 2012-01-08, accepted in 2012-08-15, 发布年份 2012 | |
【 摘 要 】
Introduction
Cerebral venous sinus thrombosis is a rare condition. The most frequent symptoms and signs are headache, focal seizures with or without secondary generalization, unilateral or bilateral paresis and papilledema. We report a case of transverse sinus and superior sagittal sinus thrombosis that presented with diplopia in a pregnant woman.
Case presentation
A 34-year-old Malay woman, gravida 3 para 2 at 8 weeks of pregnancy, was admitted for hyperemesis gravidarum, presented with sudden onset of diplopia, blurring of vision and headache. A magnetic resonance scan of her brain showed the presence of cerebral edema with no space occupying lesion, but magnetic resonance venography ultimately revealed right transverse sinus and superior sagittal sinus thrombosis. The patient was treated with anticoagulation for 1 year, after which the patient recovered fully.
Conclusion
Due to its diverse and varied neurological presentation, cerebral venous sinus thrombosis should be considered in almost any brain syndrome.
【 授权许可】
2012 Munira et al.; licensee BioMed Central Ltd.
【 预 览 】
Files | Size | Format | View |
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20150521094533532.pdf | 912KB | download | |
Figure 3. | 80KB | Image | download |
Figure 2. | 86KB | Image | download |
Figure 1. | 123KB | Image | download |
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【 参考文献 】
- [1]Cantu C, Barinagarrementeria F: Cerebral venous thrombosis associated with pregnancy and puerperium: review of 67 cases. Stroke 1993, 24:1880-1884.
- [2]Lim YH: Aseptic cerebral venous sinus thrombosis in early pregnancy. Hong Kong J Emerg Med 2007, 14:237-239.
- [3]de Bruijn SFTM, de Haan RJ, Stam J, for the Cerebral Venous Sinus Thrombosis Study Group: Clinical features and prognostic factors of cerebral venous sinus thrombosis in a prospective series of 59 patients. J Neurol Neurosurg Psychiatry 2001, 70:105-108.
- [4]Lemke DM, Hacein-Bey L: Cerebral venous sinus thrombosis. J Neurosci Nurs 2005, 37(5):258-264.
- [5]Ferro JM, Canhao P, Stam J, Bousser MG, Barinagarrementeria F, for the ISCVT Investigators: Prognosis of cerebral vein and dural sinus thrombosis – results of International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke 2004, 35:664-670.
- [6]Allroggen H, Abbott RJ: Cerebral venous sinus thrombosis. Postgrad Med J 2000, 76(891):12-15.
- [7]Tanislav C, Siekmann R, Sieweke N, Allendorfer J, Pabst W, Kaps M, Stolz E: Cerebral vein thrombosis: clinical manifestation and diagnosis. BMC Neurology 2011, 11:69. BioMed Central Full Text
- [8]Stam J: Thrombosis of the cerebral veins and sinuses. N Engl J Med 2005, 352(17):1791-1798.
- [9]Martin PJ, Enevoldson TP: Cerebral venous thrombosis. Postgrad Med J 1996, 72:72-76.
- [10]Bousser MG, Chiras J, Bories J, Castaigne P: Cerebral venous thrombosis – a review of 38 cases. Stroke 1985, 16(2):199-213.
- [11]de Bruijn SF, Stam J: Randomized, placebo-controlled trial of anticoagulant treatment with low-molecular weight heparin for cerebral sinus thrombosis. Stroke 1999, 30(3):484-488.