Computerized tomography based tumor-thickness measurement is useful to predict postoperative pathological tumor thickness in oral tongue squamous cell carcinoma

Journal of Otolaryngology-Head & Neck Surgery

Michael P. Hier¹  Alex M. Mlynarek¹  Martin J. Black¹  Deeke Yolmo¹  Grégoire B. Morand¹  Frederick Laliberté¹  J. Madana¹ 

[1] Department of Otolaryngology-Head and Neck Surgery, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, 3755 Côte Ste-Catherine Road, Montreal H3T 1E2QC, Canada

关键词: Postoperative;    Measurement;    Computerized tomography;    Oral tongue;    Tumor thickness;   

Others  :  1233215
DOI  :  10.1186/s40463-015-0089-z

 received in 2015-01-29, accepted in 2015-08-31,  发布年份 2015

【 摘 要 】

Background

Tumor thickness has been shown in oral tongue squamous cell carcinoma (OTSCC) to be a predictor of cervical metastasis. The postoperative histological measurement is certainly the most accurate, but it would be of clinical interest to gain this information prior to treatment planning. This retrospective study aimed to compare the tumor thickness measurement between preoperative, CT scan, and surgical specimens .

Methods

We retrospectively included 116 OTSCC patients between 2001 and 2013. Thickness was measured on computer tomography imaging and again surgical specimens.

Results

The median age was 66 years. 62.8 % of patients were smokers with a mean of 31.4 pack-years. Positive nodal disease was reported in 41.2 %. Mean follow-up time was 33.1 months. The correlation between CT scan-based tumor thickness and surgical specimens based thickness was significant (Spearman rho = 0.755, P < 0.001).

Conclusion

Tumor thickness assessed by CT scan may provide an accurate estimation of true thickness and can be used in treatment planning.

【 授权许可】

   
2015 Madana et al.

【 图 表 】

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