Correlations between maternal and neonatal serum selenium levels in full term neonates with hypoxic ischemic encephalopathy

Italian Journal of Pediatrics

Nashwa R. Mohammed³  Mostafa A. El-Said²  Ramadan A. Mahmoud¹  Reem A. Abdel- Aziz³  Abdel-Azeem M. El-Mazary³ 

[1] Department of Pediatrics, Faculty of Medicine, Sohag University, Sohag, Egypt;Department of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt;Department of Pediatrics, Faculty of Medicine, Minia University, Minia, Egypt

关键词: Encephalopathy;    Ischemic;    Hypoxic;    Neonates;    Selenium;   

Others  :  1232054
DOI  :  10.1186/s13052-015-0185-8

 received in 2015-07-07, accepted in 2015-10-05,  发布年份 2015

【 摘 要 】

Perinatal hypoxic-ischemic encephalopathy (HIE) is an important cause of brain injury in the newborn and can result devastating consequences. The principle mechanisms underlying neurological damage in HIE resulting from hypoxemia and/or ischemia is deprivation of glucose and oxygen supply which energy failure. A consequent reperfusion injury often deteriorates the brain metabolism by increasing the oxidative stress damage. Selenium is a constituent of the antioxidant enzyme Glutathione peroxidase and is vital to antioxidant defense. This study aimed to measure the serum selenium levels in full term neonates with HIE and their mothers and to correlate between them and the severity of HIE.

【 授权许可】

   
2015 El-Mazary et al.

【 图 表 】

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