Sex, gender and immunosenescence: a key to understand the different lifespan between men and women?

Immunity & Ageing

Giuseppina Candore¹  Claudia Virruso¹  Giulia Accardi¹  Calogero Caruso¹ 

[1] Department of Pathobiology and Medical and Forensic Biotechnologies, University of Palermo, Corso Tukory 211, Palermo 90134, Italy

关键词: Immunosenescence;    Ageing;    Gender;    Sex;   

Others  :  815006
DOI  :  10.1186/1742-4933-10-20

 received in 2013-04-21, accepted in 2013-04-21,  发布年份 2013

【 授权许可】

   
2013 Caruso et al.; licensee BioMed Central Ltd.

【 参考文献 】

• [1]World population prospects: the 2010 Revision. 2010. http://esa.un.org/wpp/ webcite
• [2]Candore G, Balistreri RC, Colonna-Romano G, Lio D, Listì F, Vasto S, Caruso C: Gender-Related Immune-Inflammatory Factors, Age-Related Diseases, and Longevity. Rejuvenation Res 2010, 13:292-7.
• [3]Pan Z, Chang C: Gender and the regulation of longevity: Implication for autoimmunity. Autoimmunity Review 2012, 11:6-7.
• [4]Lawrence DA, McCabe MJ Jr: Immunomodulation by metals. Int Immunopharmacol 2002, 2:293-302.
• [5]Vina J, Gambini J, Lopez-Grueso R, Abdelaziz KM, Jove M, Borras C: Females live longer than males: role of oxidative stress. Curr Pharm Des 2011, 17:3959-65.
• [6]Mendelsohn ME, Karas RH: The protective effects of estrogen on the cardiovascular system. N Engl J Med 1999, 340:1801-11.
• [7]Vasto S, Scapagnini G, Bulati M, Candore G, Castiglia L, Colonna-Romano G, Lio D, Nuzzo D, Pellicano M, Rizzo C, Ferrara N, Caruso C: Biomarkers of ageing. Front Biosci (Schol Ed) 2010, 2:392-402.
• [8]Hirokawa K, Utsuyama M, Hayashi Y, Kitagawa M, Makinodan T, Fulop T: Slower immune system aging in women versus men in the Japanese population. Immun Ageing 2013, 10:19. BioMed Central Full Text
• [9]Balistreri CR, Caruso C, Listì F, Colonna-Romano G, Lio D, Candore G: LPS-mediated production of pro/anti-inflammatory cytokines and eicosanoids in whole blood samples: biological effects of +896A/G TLR4 polymorphism in a Sicilian population of healthy subjects. Mech Ageing Dev 2011, 132:86-92.
• [10]Oertelt-Prigione S: The influence of sex and gender on the immune response. Autoimmun Rev 2012, 11:A479-85.
• [11]Viña J, Borrá C, Gambini J, Sastre J, Pallardó FV: Why females live longer than males: control of longevity by sex hormones. Sci Aging Knowledge Environ 2005, pe17.
• [12]Caruso C, Candore G, Romano GC, Lio D, Bonafè M, Valensin S, Franceschi C: Immunogenetics of longevity. Is major histocompatibility complex polymorphism relevant to the control of human longevity? A review of literature data. Mech Ageing Dev 2001, 122:445-62.
• [13]Ansar AS, Penhale WJ, Talal N: Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action. Am J Pathol 1985, 121:531-551.
• [14]Tower J, Arbeitman M: The genetics of gender and life span. J Biol 2009, 8:38. BioMed Central Full Text
• [15]Christensen K, Kristiansen M, Hagen-Larsen H, Skytthe A, Bathum L, Jeune B, Andersen-Ranberg K, Vaupel JW, Orstavik KH: X-linked genetic factors regulate hematopoietic stem-cell kinetics in females. Blood 2000, 95:2449-51.
• [16]Ellegren H, Parsch J: The evolution of sex-biased genes and sex-biased gene expression. Nat Rev Genet 2007, 8:689-98.
• [17]Barrett EL, Richardson DS: Sex differences in telomeres and lifespan. Aging Cell 2011, 10:913-21.
• [18]Anogeianaki A, Castellani ML, Tripodi D, Toniato E, De Lutiis MA, Conti F, Felaco P, Fulcheri M, Theoharides TC, Galzio R, Caraffa A, Antinolfi P, Cuccurullo C, Ciampoli C, Felaco M, Cerulli G, Pandolfi F, Sabatino G, Neri G, Shaik-Dasthagirisaheb YB: Vitamins and mast cells. Int J Immunopathol Pharmacol 2010, 23:991-6.
• [19]Fraker PJ, King LE: Reprogramming of the immune system during zinc deficiency. Annu Rev Nutr 2004, 24:277-98.
• [20]Bonham M, O’Connor JM, Hannigan BM, Strain JJ: The immune system as a physiological indicator of marginal copper status? Br J Nutr 2002, 87:393-403.
• [21]Ojanuga DN, Gilbert C: Women’s access to health care in developing countries. Soc Sci Med 1992, 35:613-7.
• [22]Franceschi C, Motta L, Motta M, Malaguarnera M, Capri M, Vasto S, Candore G, Caruso C, IMUSCE: The extreme longevity: the state of the art in Italy. Exp Gerontol 2008, 43:45-52.