期刊论文详细信息
Journal of Cardiothoracic Surgery
Sternal reconstruction for unusual chondrosarcoma: innovative technique
Luigi Santambrogio2  Antonina Parafioriti1  Alessandro Palleschi2  Davide Tosi2  Paolo Mendogni2  Lorenzo Rosso2  Mario Nosotti2 
[1] Pathology Department, Orthopaedic Institute Gaetano Pini, Milan, Italy;Thoracic Surgery and Lung Transplantation Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Via Francesco Sforza, 35, Milan, 20122, Italy
关键词: Transplantation;    Sternum;    Chondrosarcoma;   
Others  :  1153269
DOI  :  10.1186/1749-8090-7-40
 received in 2011-10-31, accepted in 2012-05-02,  发布年份 2012
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【 摘 要 】

The authors report a clinical case of a primary sternal chondrosarcoma, presented as a mass in the anterior mediastinum. The patient was treated with subtotal sternectomy and sternal transplantation followed by radiotherapy. Twelve months after surgery, the patient is in good clinical condition, without any sign of tumor relapse and with normal respiratory mechanics.

Primary malignant tumors of the sternum are uncommon and a presentation mimicking thymoma is rare and unreported. The stermal replacement with a cryopreserved allograft sternum is an innovative technique that overcomes the problems related to the prosthetic biocompatibility or to the bone autograft.

【 授权许可】

   
2012 Nosotti et al; licensee BioMed Central Ltd.

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【 参考文献 】
  • [1]Somers J, Faber LP: Chondroma and chondrosarcoma. Semin Thorac Cardiovasc Surg 1999, 11:270-277.
  • [2]Chapelier AR, Missana MC, Couturaud B, et al.: Sternal resection and reconstruction for primary malignant tumors. Ann Thorac Surg 2004, 77:1001-1006.
  • [3]Ashford RU, Stanton J, Khan F, Pringle JA, Cannon SR, Briggs TW: Surgical treatment of chondrosarcoma of the sternum. Sarcoma 2001, 5:209-213.
  • [4]Granero-Molto F, Weis JA, Longobardi L, Spagnoli A: Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair. Expert Opin Biol Ther 2008, 8:255-268.
  • [5]Marulli G, Hamad AM, Cogliati E, Breda C, Zuin A, Rea F: Allograft sternochondral replacement after resection of large sternal chondrosarcoma. J Thorac Cardiovasc Surg 2010, 139:e69-e70.
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