Melatonin: a potential intervention for hepatic steatosis

Lipids in Health and Disease

Shen Qu¹  Fang-fang Huang¹  Hang Sun¹ 

[1] Department of Endocrinology and Metabolism, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, China

关键词: NAFLD;    Lipid metabolism;    Melatonin;   

Others  :  1221316
DOI  :  10.1186/s12944-015-0081-7

 received in 2015-01-17, accepted in 2015-07-14,  发布年份 2015

【 摘 要 】

Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a neuroendocrine hormone, which is primarily synthesized by the pineal gland in vertebrates. Melatonin is a remarkable molecule with diverse biological and physiological actions and is involved in the regulation of various important functions such as circadian rhythm, energy metabolism, the reproductive system, the cardiovascular system, and the neuropsychiatric system. It also plays a role in disease by having anti-neoplastic and anti-osteoarthritic effects among others. Recently, research has focused on the roles of melatonin in oxidative stress, lipid metabolism, and hepatic steatosis and its potential therapeutic roles.

【 授权许可】

   
2015 Sun et al.

【 图 表 】

Fig. 1.

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